Sfoglia per Autore
7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: Structural investigations at the 5-position to target human A1 and A2A adenosine receptors. Molecular modeling and pharmacological studies
2014 Lucia Squarcialupi; Vittoria Colotta; Daniela Catarzi; Flavia Varano; Betti Marco; Katia Varani; Fabrizio Vincenzi; Pier Andrea Borea; Nicola Porta; Antonella Ciancetta; Stefano Moro
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII.
2015 Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V.
Thiazolo[5,4-d]pyrimidin-7-amino derivatives as dual human adenosine A2A/A1 receptor antagonists.
2015 Catarzi, D.; Colotta, V.; Betti, M.; Falsini, M.; Dal Ben, D.; Marucci, G.; Buccioni, M.; Varano, F.
Aminopyridine-3,5-dicarbonitriles as non-nucleoside adenosine A1 receptor agonists.
2015 Betti, Marco; Catarzi, Daniela; Varano, Flavia; Varani, Katia; Lorenzo Di Cesare Mannelli, ; Zanardelli, M.; Ghelardini, Carla; Colotta, Vittoria .
1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies
2015 Daniela Catarzi ; Flavia Varano; Daniela Poli ; Lucia Squarcialupi; Marco Betti ; Letizia Trincavelli; Claudia Martini ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta
Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation
2015 Flavia Varano; Daniela Catarzi ; Lucia Squarcialupi ; Marco Betti ; Fabrizio Vincenzi ; Annalisa Ravani ; Katia Varani ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta
Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor
2016 Lucia Squarcialupi ; Daniela Catarzi ; Flavia Varano; Marco Betti; Matteo Falsini; Fabrizio Vincenzi ; Annalisa Ravani; Antonella Ciancetta ; Katia Varani ; Stefano Moro; Vittoria Colotta
Design, synthesis, and pharmacological characterization of 2‑(2- furanyl)thiazolo[5,4‑d]pyrimidine-5,7-diamine derivatives: new highly potent A2A adenosine receptor inverse agonists with antinociceptive activity
2016 Flavia Varano; Daniela Catarzi; Fabrizio Vincenzi; Marco Betti; Matteo Falsini; Annalisa Ravani; Pier Andrea Borea; Vittoria Colotta; Katia Varani
New 5-heteroaryl-pyrazolo[4,3-d]pyrimidin-7-amines as dual human adenosine A1 and A2A receptor antagonists.
2016 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Lambertucci, Catia; Volpini, Rosaria; Colotta, Vittoria
New aminopyridine-3,5-dicarbonitirles as adenosine A2B receptor non-nucleoside agonists.
2016 Betti, Marco; Colotta, Vittoria; Varano, Flavia; Falsini, Matteo; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Pugliese, Annamaria; Catarzi, Daniela
Aminopyridine-3,5-carbonitrile core for the design of new adenosine receptor agonists: structural exploration to target the A1 subtype
2016 Betti, M.; Colotta, V.; Varano, F.; Falsini, M.; Varani, K.; Vincenzi, F.; Dal Ben, D.; Di Cesare Mannelli, L.; Zanardelli, M.; Bartolucci, G.; Menicatti, M.; Catarzi, D.
2-Aryl-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as new potent adenosine human A2A receptor antagonists
2016 Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Dal Ben, D.; Marucci, G.; Buccioni, M.; Volpini, R.; De Vita, T.; Colotta, V. .
Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors
2016 Lucia Squarcialupi; Matteo Falsini; Daniela Catarzi; Flavia Varano; Marco Betti; Katia Varani; Fabrizio Vincenzi; Diego Dal Ben; Catia Lambertucci; Rosaria Volpini; Vittoria Colotta
Design, synthesis and pharmacological evaluation of new adenosine receptor ligands
2017 Betti, Marco
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII
2017 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype
2017 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Dal Ben, Diego; Marucci, Gabriella; Buccioni, Michela; Volpini, Rosaria; De Vita, Teresa; Cavalli, Andrea; Colotta, Vittoria
Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A3 and A2A subtypes
2017 Daniela Poli, ; Matteo Falsini, ; Flavia Varano, ; Marco Betti, ; Katia Varani, ; Fabrizio Vincenzi, ; Anna Maria Pugliese, ; Felicita Pedata, ; Diego Dal Ben, ; Ajiroghene Thomas, ; Ilaria Palchetti, ; Francesca Bettazzi, ; Daniela Catarzi, ; Colotta, Vittoria
The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles
2017 Squarcialupi, Lucia; Betti, Marco; Catarzi, Daniela; Varano, Flavia; Falsini, Matteo; Ravani, Annalisa; Pasquini, Silvia; Vincenzi, Fabrizio; Salmaso, Veronica; Sturlese, Mattia; Varani, Katia; Moro, Stefano; Colotta, Vittoria
The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2Breceptor
2018 Betti, Marco; Catarzi, Daniela; Varano, Flavia; Falsini, Matteo; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Lambertucci, Catia; Colotta, Vittoria
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: Structural investigations at the 5-position to target human A1 and A2A adenosine receptors. Molecular modeling and pharmacological studies | 2014 | Lucia Squarcialupi; Vittoria Colotta; Daniela Catarzi; Flavia Varano; Betti Marco; Katia Varani; Fabrizio Vincenzi; Pier Andrea Borea; Nicola Porta; Antonella Ciancetta; Stefano Moro | |
| 3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII. | 2015 | Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V. | |
| Thiazolo[5,4-d]pyrimidin-7-amino derivatives as dual human adenosine A2A/A1 receptor antagonists. | 2015 | Catarzi, D.; Colotta, V.; Betti, M.; Falsini, M.; Dal Ben, D.; Marucci, G.; Buccioni, M.; Varano, F. | |
| Aminopyridine-3,5-dicarbonitriles as non-nucleoside adenosine A1 receptor agonists. | 2015 | Betti, Marco; Catarzi, Daniela; Varano, Flavia; Varani, Katia; Lorenzo Di Cesare Mannelli, ; Zanardelli, M.; Ghelardini, Carla; Colotta, Vittoria . | |
| 1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies | 2015 | Daniela Catarzi ; Flavia Varano; Daniela Poli ; Lucia Squarcialupi; Marco Betti ; Letizia Trincavelli; Claudia Martini ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta | |
| Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation | 2015 | Flavia Varano; Daniela Catarzi ; Lucia Squarcialupi ; Marco Betti ; Fabrizio Vincenzi ; Annalisa Ravani ; Katia Varani ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta | |
| Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor | 2016 | Lucia Squarcialupi ; Daniela Catarzi ; Flavia Varano; Marco Betti; Matteo Falsini; Fabrizio Vincenzi ; Annalisa Ravani; Antonella Ciancetta ; Katia Varani ; Stefano Moro; Vittoria Colotta | |
| Design, synthesis, and pharmacological characterization of 2‑(2- furanyl)thiazolo[5,4‑d]pyrimidine-5,7-diamine derivatives: new highly potent A2A adenosine receptor inverse agonists with antinociceptive activity | 2016 | Flavia Varano; Daniela Catarzi; Fabrizio Vincenzi; Marco Betti; Matteo Falsini; Annalisa Ravani; Pier Andrea Borea; Vittoria Colotta; Katia Varani | |
| New 5-heteroaryl-pyrazolo[4,3-d]pyrimidin-7-amines as dual human adenosine A1 and A2A receptor antagonists. | 2016 | Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Lambertucci, Catia; Volpini, Rosaria; Colotta, Vittoria | |
| New aminopyridine-3,5-dicarbonitirles as adenosine A2B receptor non-nucleoside agonists. | 2016 | Betti, Marco; Colotta, Vittoria; Varano, Flavia; Falsini, Matteo; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Pugliese, Annamaria; Catarzi, Daniela | |
| Aminopyridine-3,5-carbonitrile core for the design of new adenosine receptor agonists: structural exploration to target the A1 subtype | 2016 | Betti, M.; Colotta, V.; Varano, F.; Falsini, M.; Varani, K.; Vincenzi, F.; Dal Ben, D.; Di Cesare Mannelli, L.; Zanardelli, M.; Bartolucci, G.; Menicatti, M.; Catarzi, D. | |
| 2-Aryl-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as new potent adenosine human A2A receptor antagonists | 2016 | Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Dal Ben, D.; Marucci, G.; Buccioni, M.; Volpini, R.; De Vita, T.; Colotta, V. . | |
| Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors | 2016 | Lucia Squarcialupi; Matteo Falsini; Daniela Catarzi; Flavia Varano; Marco Betti; Katia Varani; Fabrizio Vincenzi; Diego Dal Ben; Catia Lambertucci; Rosaria Volpini; Vittoria Colotta | |
| Design, synthesis and pharmacological evaluation of new adenosine receptor ligands | 2017 | Betti, Marco | |
| 3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII | 2017 | Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria | |
| The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype | 2017 | Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Dal Ben, Diego; Marucci, Gabriella; Buccioni, Michela; Volpini, Rosaria; De Vita, Teresa; Cavalli, Andrea; Colotta, Vittoria | |
| Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A3 and A2A subtypes | 2017 | Daniela Poli, ; Matteo Falsini, ; Flavia Varano, ; Marco Betti, ; Katia Varani, ; Fabrizio Vincenzi, ; Anna Maria Pugliese, ; Felicita Pedata, ; Diego Dal Ben, ; Ajiroghene Thomas, ; Ilaria Palchetti, ; Francesca Bettazzi, ; Daniela Catarzi, ; Colotta, Vittoria | |
| The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles | 2017 | Squarcialupi, Lucia; Betti, Marco; Catarzi, Daniela; Varano, Flavia; Falsini, Matteo; Ravani, Annalisa; Pasquini, Silvia; Vincenzi, Fabrizio; Salmaso, Veronica; Sturlese, Mattia; Varani, Katia; Moro, Stefano; Colotta, Vittoria | |
| The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2Breceptor | 2018 | Betti, Marco; Catarzi, Daniela; Varano, Flavia; Falsini, Matteo; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Lambertucci, Catia; Colotta, Vittoria |
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