Sfoglia per Autore
Exploiting soft and hard x-ray absorption spectroscopy to characterize metallodrug/protein interactions: the binding of [trans-rucl4(im)(dimethylsulfoxide)][imH] (im = imidazole) to bovine serum albumin
2008 I. Ascone; L. Messori; A. Casini; C. Gabbiani; A. Balerna; F. Dell'unto; A.C. Castellano
The influence of auranofin, a clinically established antiarthritic gold drug, on bone metabolism: analysis of its effects on human multipotent adipose-derived stem cells, taken as a model
2008 C. Chiellini; A. Casini; O. Cochet; C. Gabbiani; G. Ailhaud; C. Dani; L. Messori; E.Z. Amri
Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from x-ray diffraction and mass spectrometry studies.
2008 A. Casini; A. Guerri; C. Gabbiani; L. Messori
New uses for old drugs. auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: mechanistic and pharmacological implications
2008 A.R. Sannella; A. Casini; C. Gabbiani; L. Messori; A.R. Bilia; F.F. Vincieri; G. Majori; C. Severini
Antiplasmodial Effects of a few Selected Natural Flavonoids and their Modulation of Artemisinin Activity
2008 A.R. Bilia; A.R. Sannella; F.F. Vincieri; L. Messori; A. Casini; C. Gabbiani ; C. Severini; G. Majori
GOLD(III) COMPOUNDS AS ANTICANCER AGENTS: RELEVANCE OF GOLD-PROTEIN INTERACTIONS FOR THE MECHANISM OF ACTION
2008 A. CASINI; C. HARTINGER; C. GABBIANI ; E. MINI; P.J. DYSON; B.K. KEPPLER; L. MESSORI
Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions
2009 C. Gabbiani
Exploring metal complexes-protein/peptide interactions by high resolution mass spectrometry
2009 Elena Michelucci, Chiara Gabbiani, Angela Casini, Giuseppe Pieraccini, Gloriano Moneti, Daniela Valensin, Luigi Messori
Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease.
2009 C. Grossi;S. Francese;A. Casini;M. C. Rosi;I. Luccarini;A. Fiorentini;C. Gabbiani;L. Messori;G. Moneti;F. Casamenti
Trans-cis-cis-[RuCl(2)(DMSO)(2)(2-amino-5-methyl-thiazole)(2)], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B.
2009 P. Mura;M. Camalli;A. Casini;C. Gabbiani;L. Messori
Proanthocyanidin glycosides from the leaves of Quercus ilex L. (Fagaceae)
2009 Karioti A.; Bilia A.R.; Gabbiani C.; Messori L.; Skaltsa H.
Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound.
2009 A. Casini;C. Gabbiani;E. Michelucci;G. Pieraccini;G. Moneti;P. J. Dyson;L. Messori
Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study.
2009 A. Casini;G. Kelter;C. Gabbiani;M. A. Cinellu;G. Minghetti;D. Fregona;H. Fiebig;L. Messori
Exploring the interactions of a “rule-breaker” iodo-platinum(II) complex with cytochrome c by mass spectrometry
2010 Michelucci E., Messori L., Casini A., Gabbiani C., Moneti G., Cubo L., Ríos-Luci C., Padrón J. M., Navarro-Ranninger C., Quiroga A. G.
fac-Ru(CO)(3)(2+) selectively targets the histidine residues of the beta-amyloid peptide 1-28. Implications for new Alzheimer's disease treatments based on ruthenium complexes.
2010 D. Valensin; P. Anzini; E. Gaggelli; N. Gaggelli; G. Tamasi; R. Cini; C. Gabbiani; E. Michelucci; L. Messori; H. Kozlowski; G. Valensin
The X-ray Structure of the Adduct between NAMI-A and CarbonicAnhydrase Provides Insights into the Reactivity of this Metallodrug with Proteins
2010 A.Casini; C.Temperini; C.Gabbiani; C.Supuran; L.Messori
Reactions of medicinally relevant gold compounds with the C-terminal motif of thioredoxin reductase elucidated by MS analysis.
2010 A. Pratesi;C. Gabbiani;M. Ginanneschi;L. Messori
Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study.
2010 F. Magherini; A. Modesti; L. Bini; M. Puglia; I. Landini; S. Nobili; E. Mini; M.A. Cinellu; C. Gabbiani; L. Messori
Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies.
2010 Nobili S; Mini E; Landini I; Gabbiani C; Casini A; Messori L.
Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study.
2010 Magherini F; Modesti A; Bini L; Puglia M; Landini I; Nobili S; Mini E; Cinellu MA; Gabbiani C; Messori L.
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