Metabolomics – the study of metabolites and low-molecular-weight intermediate molecules – provides the support for deepening and strengthening the understanding of the basic processes of living organisms. Metabolomics has established itself as a useful complement to the characterization of pathologies because it allows the identification of critical metabolic pathways involved in biochemical processes. NMR-based metabolomics offers evident advantages over the knowledge-guided search of metabolites. In fact, the dynamic, simultaneous assessment of thousands of metabolites allows the definition of a physiopathological-related metabolic fingerprint through the statistical analysis of NMR profiles.
Metabolomics / Tenori, Leonardo. - STAMPA. - (2012), pp. 466-477. [10.1002/9783527644506.ch28]
Metabolomics
TENORI, LEONARDO
2012
Abstract
Metabolomics – the study of metabolites and low-molecular-weight intermediate molecules – provides the support for deepening and strengthening the understanding of the basic processes of living organisms. Metabolomics has established itself as a useful complement to the characterization of pathologies because it allows the identification of critical metabolic pathways involved in biochemical processes. NMR-based metabolomics offers evident advantages over the knowledge-guided search of metabolites. In fact, the dynamic, simultaneous assessment of thousands of metabolites allows the definition of a physiopathological-related metabolic fingerprint through the statistical analysis of NMR profiles.
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