Background: During the last decades remarkable scientific advances have been made toward the prevention of HIV mother-to-child transmission, in particular in developed nations. The aim of this review was to analyze the latest findings and available international recommendations on the prevention of HIV mother-to-child transmission in high-income countries. Methods: We performed a literature search of the Cochrane Library, MEDLINE by PubMed and EMBASE from database inception through June 2014, using the following terms: HIV, mother-to-child transmission and mother-to-child-transmission prevention. All types of articles in the English language were included. US and available European guidelines were searched and included in the analysis. Results: One hundred fifty articles were selected for inclusion in this review. Conclusions: Global epidemiology of HIV infection is rapidly evolving, in particular in high-resource countries. The interpretation of clinical and epidemiological studies is crucial for the development of evidence-based recommendations to guide the management of HIV mother-to-child transmission. Although significant progress has been made, heterogeneity between countries in specific interventions still exists, which may address future research.
Strategies for the prevention of mother to child transmission in Western countries: an update / Sollai, Sara; Noguera-Julian, Antoni; Galli, Luisa; Fortuny, Clàudia; Deyà, Ángela; De Martino, Maurizio; Chiappini, Elena. - In: THE PEDIATRIC INFECTIOUS DISEASE JOURNAL. - ISSN 0891-3668. - STAMPA. - 34:(2015), pp. S14-S30. [10.1097/INF.0000000000000661]
Strategies for the prevention of mother to child transmission in Western countries: an update
GALLI, LUISA;DE MARTINO, MAURIZIO;CHIAPPINI, ELENA
2015
Abstract
Background: During the last decades remarkable scientific advances have been made toward the prevention of HIV mother-to-child transmission, in particular in developed nations. The aim of this review was to analyze the latest findings and available international recommendations on the prevention of HIV mother-to-child transmission in high-income countries. Methods: We performed a literature search of the Cochrane Library, MEDLINE by PubMed and EMBASE from database inception through June 2014, using the following terms: HIV, mother-to-child transmission and mother-to-child-transmission prevention. All types of articles in the English language were included. US and available European guidelines were searched and included in the analysis. Results: One hundred fifty articles were selected for inclusion in this review. Conclusions: Global epidemiology of HIV infection is rapidly evolving, in particular in high-resource countries. The interpretation of clinical and epidemiological studies is crucial for the development of evidence-based recommendations to guide the management of HIV mother-to-child transmission. Although significant progress has been made, heterogeneity between countries in specific interventions still exists, which may address future research.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.