PURPOSE: To report for the first time a case report of a Stargardt disease patient who developed a macular hole (MH) which was treated with a surgical approach. METHOD: Case report. RESULTS: After vitrectomy a complete closure of the MH was obtained and the best-corrected visual acuity remained stable. No complications were reported after one year of follow-up. An ultra-structural examination of the removed internal limiting membrane (ILM) and epiretinal membrane (ERM) was carried out under electron microscopy. CONCLUSION: Vitreo-retinal surgery could represent a therapeutic option to treat vitreo-retinal interface abnormalities associated with inherited retinal diseases.
Macular hole in Stargardt disease: Clinical and ultra-structural observation / Rizzo, Stanislao; Mucciolo, Dario Pasquale*; Bacherini, Daniela; Murro, Vittoria; Vannozzi, Lorenzo; Virgili, Gianni; Bani, Daniele; Sodi, Andrea. - In: OPHTHALMIC GENETICS. - ISSN 1381-6810. - ELETTRONICO. - 38:(2017), pp. 486-489. [10.1080/13816810.2016.1266666]
Macular hole in Stargardt disease: Clinical and ultra-structural observation
Rizzo, Stanislao;Mucciolo, Dario Pasquale;Bacherini, Daniela;Murro, Vittoria;Vannozzi, Lorenzo;Virgili, Gianni;Bani, Daniele;Sodi, Andrea
2017
Abstract
PURPOSE: To report for the first time a case report of a Stargardt disease patient who developed a macular hole (MH) which was treated with a surgical approach. METHOD: Case report. RESULTS: After vitrectomy a complete closure of the MH was obtained and the best-corrected visual acuity remained stable. No complications were reported after one year of follow-up. An ultra-structural examination of the removed internal limiting membrane (ILM) and epiretinal membrane (ERM) was carried out under electron microscopy. CONCLUSION: Vitreo-retinal surgery could represent a therapeutic option to treat vitreo-retinal interface abnormalities associated with inherited retinal diseases.
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