Feto-placental unit represents an important source of activin A, a member of transforming growth factors-β involved in the mechanisms of labor. No evidences are available on activin A in pregnancies beyond 41 weeks of gestation, where induction of labor is often required. The present study aimed to evaluate activin A maternal serum levels and placental mRNA expression in term and late-term pregnancy, with spontaneous or induced labor, and its possible role to predict the response to labor induction.
Placental and maternal serum activin A in spontaneous and induced labor in late-term pregnancy / Funghi, L; Torricelli, M; Novembri, R; Vannuccini, S; Cevenini, G; Di Tommaso, M; Severi, F M; Petraglia, F. - In: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. - ISSN 1720-8386. - ELETTRONICO. - (2017), pp. 1-7. [10.1007/s40618-017-0640-z]
Placental and maternal serum activin A in spontaneous and induced labor in late-term pregnancy
Vannuccini, S;DI TOMMASO, MARIAROSARIA;PETRAGLIA, FELICE
2017
Abstract
Feto-placental unit represents an important source of activin A, a member of transforming growth factors-β involved in the mechanisms of labor. No evidences are available on activin A in pregnancies beyond 41 weeks of gestation, where induction of labor is often required. The present study aimed to evaluate activin A maternal serum levels and placental mRNA expression in term and late-term pregnancy, with spontaneous or induced labor, and its possible role to predict the response to labor induction.
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