The regulation of food intake is a complex mechanism, and the hypothalamus is the main central structure implicated. In particular, the arcuate nucleus appears to be the most critical area in the integration of multiple peripheral signals. Among these signals, those originating from the white adipose tissue and the gastrointestinal tract are known to be involved in the regulation of food intake. The present paper focuses on adiponectin, an adipokine secreted by white adipose tissue, which is reported to have a role in the control of feeding by acting centrally. The recent observation that adiponectin is also able to influence gastric motility raises the question of whether this action represents an additional peripheral mechanism that concurs with the central effects of the hormone on food intake. This possibility, which represents an emerging aspect correlating the central and peripheral effects of adiponectin in the hunger-satiety cycle, is discussed in the present paper.

Can adiponectin have an additional effect on the regulation of food intake by inducing gastric motor changes? / Idrizaj E.; Garella R.; Squecco R.; Baccari M.C.. - In: WORLD JOURNAL OF GASTROENTEROLOGY. - ISSN 2219-2840. - ELETTRONICO. - 26:(2020), pp. 2472-2478. [10.3748/wjg.v26.i20.2472]

Can adiponectin have an additional effect on the regulation of food intake by inducing gastric motor changes?

Idrizaj E.;Garella R.;Squecco R.;Baccari M. C.
2020

Abstract

The regulation of food intake is a complex mechanism, and the hypothalamus is the main central structure implicated. In particular, the arcuate nucleus appears to be the most critical area in the integration of multiple peripheral signals. Among these signals, those originating from the white adipose tissue and the gastrointestinal tract are known to be involved in the regulation of food intake. The present paper focuses on adiponectin, an adipokine secreted by white adipose tissue, which is reported to have a role in the control of feeding by acting centrally. The recent observation that adiponectin is also able to influence gastric motility raises the question of whether this action represents an additional peripheral mechanism that concurs with the central effects of the hormone on food intake. This possibility, which represents an emerging aspect correlating the central and peripheral effects of adiponectin in the hunger-satiety cycle, is discussed in the present paper.
2020
26
2472
2478
Goal 3: Good health and well-being for people
Idrizaj E.; Garella R.; Squecco R.; Baccari M.C.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1199180
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