The new fluorescent lipophilic moiety 11-[(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-acetyl)amino]undecanoic acid (AMCA-oAud-OH) was introduced by SPPS at the N-terminus of the immunodominant epitope GpMBP(74–85). FRET experiments using the new fluorescent lipopeptide demonstrate that the peptide interacts with much more affinity with the membrane compared to the lipid free analogue,

A new lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models / PERONI E.; CAMINATI G.; P. BAGLIONI; NUTI F.; CHELLI M.; PAPINI A. M.. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - STAMPA. - 12:(2002), pp. 1731-1734.

A new lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models

CAMINATI, GABRIELLA;BAGLIONI, PIERO;NUTI, FRANCESCA;PAPINI, ANNA MARIA
2002

Abstract

The new fluorescent lipophilic moiety 11-[(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-acetyl)amino]undecanoic acid (AMCA-oAud-OH) was introduced by SPPS at the N-terminus of the immunodominant epitope GpMBP(74–85). FRET experiments using the new fluorescent lipopeptide demonstrate that the peptide interacts with much more affinity with the membrane compared to the lipid free analogue,
2002
12
1731
1734
PERONI E.; CAMINATI G.; P. BAGLIONI; NUTI F.; CHELLI M.; PAPINI A. M.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/200622
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