The asymmetry of the blood flow in the human left ventricle is commonly assumed to facilitate the following ejection of blood in the primary circulation. The intraventricular flow is here studied by the numerical solution of the governing equations written in a prolate spheroid geometry with moving walls. The physiological parameters are taken from pediatric clinical data; then, the entering jet is artificially displaced to modify the asymmetry of the flow. The analysis of flow patterns confirms that the physiological case looks to best comply with the transition from the filling to the ejection phase. The flow energy dissipation is found to be minimized about the physiological conditions. An unnatural asymmetry, as given by cardiac diseases or valvular replacement, could reduce the efficiency of the heart pump by over 10%, thus augmenting the work required by the cardiac muscle.

Nature optimizes the swirling flow in the left ventricle / G. PEDRIZZETTI.; F. DOMENICHINI. - In: PHYSICAL REVIEW LETTERS. - ISSN 0031-9007. - STAMPA. - 95:(2005), pp. 108101-108105. [10.1103/PhysRevLett.95.108101]

Nature optimizes the swirling flow in the left ventricle

DOMENICHINI, FEDERICO
2005

Abstract

The asymmetry of the blood flow in the human left ventricle is commonly assumed to facilitate the following ejection of blood in the primary circulation. The intraventricular flow is here studied by the numerical solution of the governing equations written in a prolate spheroid geometry with moving walls. The physiological parameters are taken from pediatric clinical data; then, the entering jet is artificially displaced to modify the asymmetry of the flow. The analysis of flow patterns confirms that the physiological case looks to best comply with the transition from the filling to the ejection phase. The flow energy dissipation is found to be minimized about the physiological conditions. An unnatural asymmetry, as given by cardiac diseases or valvular replacement, could reduce the efficiency of the heart pump by over 10%, thus augmenting the work required by the cardiac muscle.
2005
95
108101
108105
G. PEDRIZZETTI.; F. DOMENICHINI
File in questo prodotto:
File Dimensione Formato  
2005PRL.pdf

Accesso chiuso

Tipologia: Versione finale referata (Postprint, Accepted manuscript)
Licenza: Tutti i diritti riservati
Dimensione 744.5 kB
Formato Adobe PDF
744.5 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/207496
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 218
  • ???jsp.display-item.citation.isi??? 195
social impact