Accumulation of extracellular matrix in the mesangium and altered renal eicosanoid synthesis are two prominent features of diabetic glomerular disease. Our data also indicate that glucose-enhanced mesangial matrix accumulation may be prevented by exogenous PGE2 or by drugs capable of increasing endogenous PGE2 synthesis
Regulatory role of eicosanoids in extracellular matrix overproduction induced by long-term exposure to high glucose in cultured rat mesangial cells / F. PRICCI; G. PUGLIESE; P. MENE’; G. ROMEO; G. ROMANO; G. GALLI; A. CASINI; C. ROTELLA; U. DI MARIO; F. PUGLIESE. - In: DIABETOLOGIA. - ISSN 0012-186X. - ELETTRONICO. - 39 (9)::(1996), pp. 1055-1062.
Regulatory role of eicosanoids in extracellular matrix overproduction induced by long-term exposure to high glucose in cultured rat mesangial cells.
ROTELLA, CARLO MARIA;
1996
Abstract
Accumulation of extracellular matrix in the mesangium and altered renal eicosanoid synthesis are two prominent features of diabetic glomerular disease. Our data also indicate that glucose-enhanced mesangial matrix accumulation may be prevented by exogenous PGE2 or by drugs capable of increasing endogenous PGE2 synthesis
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
