Hepatitis C virus (HCV), which is both a hepatotropic and a lymphotropic virus, has been proposed as a possible causative agent of mixed cryoglobulinaemia. This 'benign' lymphoproliferative disorder can switch over to a malignant B-cell non-Hodgkin's lymphoma (NHL). Therefore HCV infection has been investigated in a series of 50 unselected Italian patients with B-cell NHL. Antibodies against HCV were found in 30% of NHL and HCV viraemia in 32% of cases. HCV-related markers were detected in 34% (17/50) of our NHL patients; this prevalence is particularly significant when compared with HCV seropositivity in Hodgkin's lymphoma (3%) and healthy controls (1.3%).

Hepatitis C virus infection in patients with non-Hodgkin's lymphoma / C. Ferri; F. Caracciolo; A.L. Zignego; L. La Civita; M. Monti; G. Longombardo; F. Lombardini; F. Greco; E. Capochiani; A. Mazzoni; C. Mazzaro; G. Pasero. - In: BRITISH JOURNAL OF HAEMATOLOGY. - ISSN 0007-1048. - STAMPA. - 88:(1994), pp. 392-394.

Hepatitis C virus infection in patients with non-Hodgkin's lymphoma

ZIGNEGO, ANNA LINDA;MONTI, MONICA;
1994

Abstract

Hepatitis C virus (HCV), which is both a hepatotropic and a lymphotropic virus, has been proposed as a possible causative agent of mixed cryoglobulinaemia. This 'benign' lymphoproliferative disorder can switch over to a malignant B-cell non-Hodgkin's lymphoma (NHL). Therefore HCV infection has been investigated in a series of 50 unselected Italian patients with B-cell NHL. Antibodies against HCV were found in 30% of NHL and HCV viraemia in 32% of cases. HCV-related markers were detected in 34% (17/50) of our NHL patients; this prevalence is particularly significant when compared with HCV seropositivity in Hodgkin's lymphoma (3%) and healthy controls (1.3%).
1994
88
392
394
C. Ferri; F. Caracciolo; A.L. Zignego; L. La Civita; M. Monti; G. Longombardo; F. Lombardini; F. Greco; E. Capochiani; A. Mazzoni; C. Mazzaro; G. Pasero
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/226183
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