A general approach that allows reliable detection of a single base-pair mismatch is pre- sented. Specifically, how important a careful design of the allele-specific oligonucleotide (ASO) probe is, was demonstrated for a G·T mispair highly stable from the thermodynamic point of view.

Design of an optimal allele-specific oligonucleotide probe for the efficient discrimination of a thermodynamically stable (G*T) mismatch / Lucarelli Fausto; Marrazza Giovanna; Mascini Marco;. - In: ANALYTICA CHIMICA ACTA. - ISSN 0003-2670. - STAMPA. - 603 (1):(2007), pp. 82-86.

Design of an optimal allele-specific oligonucleotide probe for the efficient discrimination of a thermodynamically stable (G*T) mismatch

Lucarelli Fausto
;
Marrazza Giovanna
Supervision
;
Mascini Marco
2007

Abstract

A general approach that allows reliable detection of a single base-pair mismatch is pre- sented. Specifically, how important a careful design of the allele-specific oligonucleotide (ASO) probe is, was demonstrated for a G·T mispair highly stable from the thermodynamic point of view.
2007
603 (1)
82
86
Lucarelli Fausto; Marrazza Giovanna; Mascini Marco;
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/254326
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