The human uterus is generally considered to be an immunologically privilege site that isolates the implanted allogeneic embryo from an aggressive maternal immune response. Maternal tolerance of the fetal allograft could be the result of the integration of numerous mechanisms promoted by decidual natural killer (NK) cells, macrophages and T cells. In this review, we outline the possible role of all these immune cells on the maintenance of pregnancy, focusing on the role of the T cells.
Role of immune cells in pregnancy / M. PICCINNI. - In: AUTOIMMUNITY. - ISSN 0891-6934. - STAMPA. - 36:(2003), pp. 1-4.
Role of immune cells in pregnancy.
PICCINNI, MARIE-PIERRE
2003
Abstract
The human uterus is generally considered to be an immunologically privilege site that isolates the implanted allogeneic embryo from an aggressive maternal immune response. Maternal tolerance of the fetal allograft could be the result of the integration of numerous mechanisms promoted by decidual natural killer (NK) cells, macrophages and T cells. In this review, we outline the possible role of all these immune cells on the maintenance of pregnancy, focusing on the role of the T cells.
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