A computer method is described in which an estimate of Km and V parameters is obtained by fitting a Michaelis-Menten hyperbola to experimental data. The frequency distribution of calculated parameters is far from normality. A statistical evaluation of the differences between kinetic parameters must be obtained by the use of non-parametric statistics.
A computer method for the kinetic analysis of enzyme activity / P. Dolara; A. Agresti. - In: MONOGRAPH IN NEURONAL SCIENCES. - ISSN 0300-5186. - STAMPA. - 3:(1976), pp. 124-128.
A computer method for the kinetic analysis of enzyme activity.
DOLARA, PIERO;
1976
Abstract
A computer method is described in which an estimate of Km and V parameters is obtained by fitting a Michaelis-Menten hyperbola to experimental data. The frequency distribution of calculated parameters is far from normality. A statistical evaluation of the differences between kinetic parameters must be obtained by the use of non-parametric statistics.
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