a new derivative of carboymethilcellulse was synthetized by converting some of the carboxylic groups into amidic moieties. The procedure allowed for a good control of the degree of substitution . The new polysaccharide was also used for the realisation of a hydrolgel which showed physico-chemical properties closer to those of hyaluronan rather than native carboxymethylcellulose.Cytoxicity and biological activity were investigated on osteoblast-like cells and pancreatic cells
THE EFFECT OF AMIDIC MOIETIES ON POLISACCHARIDES: EVALUATION OF THE PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF AMIDIC CARBOXYMETHILCELLULOSE (CMCA) IN THE FORM OF LINEAR POLYMER AND HYDROGEL / R. BARBUCCI; G. LEONE; M. MONICI; D. PANTALONE; M. FINI; R. GIARDINO. - In: JOURNAL OF MATERIALS CHEMISTRY. - ISSN 0959-9428. - STAMPA. - 15:(2005), pp. 2234-2241.
THE EFFECT OF AMIDIC MOIETIES ON POLISACCHARIDES: EVALUATION OF THE PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF AMIDIC CARBOXYMETHILCELLULOSE (CMCA) IN THE FORM OF LINEAR POLYMER AND HYDROGEL
MONICI, MONICA;PANTALONE, DESIRE';
2005
Abstract
a new derivative of carboymethilcellulse was synthetized by converting some of the carboxylic groups into amidic moieties. The procedure allowed for a good control of the degree of substitution . The new polysaccharide was also used for the realisation of a hydrolgel which showed physico-chemical properties closer to those of hyaluronan rather than native carboxymethylcellulose.Cytoxicity and biological activity were investigated on osteoblast-like cells and pancreatic cells
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