A recent study has shown a mutation at codon 713 of the amyloid precursor protein (APP) gene in a schizophrenic patient. We have analyzed the MaeIII restriction site caused by that mutation in Italian and Russian families with schizophrenia. No mutations were observed suggesting that the APP713 mutation is unlikely to be linked to the pathogenesis of such a psychiatric disorder.
Absence of APP713 mutation in Italian and Russian families with schizophrenia / M.MORTILLA; L.AMADUCCI; A.BRUNI; M.P.MONTESI; A.TRUBNIKOV; S.DE CATALDO; S.PALLANTI; A.PAZZAGLI; L.GRECU; P.SERVI. - In: NEUROSCIENCE LETTERS. - ISSN 0304-3940. - STAMPA. - 165:(1994), pp. 45-47. [10.1016/0304-3940(94)90705-6]
Absence of APP713 mutation in Italian and Russian families with schizophrenia.
PALLANTI, STEFANO;
1994
Abstract
A recent study has shown a mutation at codon 713 of the amyloid precursor protein (APP) gene in a schizophrenic patient. We have analyzed the MaeIII restriction site caused by that mutation in Italian and Russian families with schizophrenia. No mutations were observed suggesting that the APP713 mutation is unlikely to be linked to the pathogenesis of such a psychiatric disorder.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.