This paper describes the development of a highly selective single-nucleotide polymorphisms (SNPs) typing method based on the use of split hybridisation probes and demonstrates the concept through the electrochemical analysis of single-base mutations in actual patient samples.
Split hybridisation probes for electrochemical typing of single-nucleotide polymorphisms / F. Lucarelli; S. Capponcelli; G. Marrazza; L. Sangiorgi; M. Mascini. - In: ANALYST. - ISSN 0003-2654. - STAMPA. - 134 (1):(2009), pp. 52-59.
Split hybridisation probes for electrochemical typing of single-nucleotide polymorphisms
LUCARELLI, FAUSTO;MARRAZZA, GIOVANNA
;MASCINI, MARCO
2009
Abstract
This paper describes the development of a highly selective single-nucleotide polymorphisms (SNPs) typing method based on the use of split hybridisation probes and demonstrates the concept through the electrochemical analysis of single-base mutations in actual patient samples.
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