Abstract—Today, there is a steadily growing interest in the use of proton beams for tumor therapy, as they permit to tightly shape the dose delivered to the target reducing the exposure of the surrounding healthy tissues. Nonetheless, accuracy in the determination of the dose distribution in proton-therapy is up to now limited by the uncertainty in stopping powers, which are presently calculated from the photon attenuation coefficients measured by X-ray tomography. Proton computed tomography apparatus (pCT) has been proposed to directly measure the stopping power and reduce this uncertainty. Main problem with proton imaging is the blurring effect introduced by multiple Coulomb scattering: single proton tracking is a promising technique to face this difficulty. As a first step towards a pCT system, we designed a proton radiography (pCR) prototype based on a silicon microstrip tracker (to characterize particle trajectories) and a segmented YAG:Ce calorimeter (to measure their residual energy). Aim of the system is to detect protons with a 1 MHz particle rate of and with kinetic energy in the range 250–270 MeV, high enough to pass through human body. Design and development of the pCR prototype, as well as the characterization of its single components, are described in this paper.

Characterization of a silicon strip detector and a YaG:Ce calorimeter for a proton computed radiography apparatus / D.Menichelli; M.Bruzzi; M.Bucciolini; G.Candiano; G.A.P.Cirrone; L. Capineri; C.Civinini; G.Cuttone; D.Lo Presti; L. Marrazzo; S. Pallotta; N.Randazzo; V.Sipala; C.Talamonti ; S.Valentini; S.Pieri; V.Reggioli; M.Brianzi; M.Tesi. - In: IEEE TRANSACTIONS ON NUCLEAR SCIENCE. - ISSN 0018-9499. - ELETTRONICO. - Volume: 57 Issue: 1 Part 1:(2010), pp. 8-16. [10.1109/TNS.2009.2031869]

Characterization of a silicon strip detector and a YaG:Ce calorimeter for a proton computed radiography apparatus

MENICHELLI, DAVID;BRUZZI, MARA;BUCCIOLINI, MARTA;CAPINERI, LORENZO
Investigation
;
MARRAZZO, LIVIA;PALLOTTA, STEFANIA;TALAMONTI, CINZIA;VALENTINI, SAMUELA
Validation
;
2010

Abstract

Abstract—Today, there is a steadily growing interest in the use of proton beams for tumor therapy, as they permit to tightly shape the dose delivered to the target reducing the exposure of the surrounding healthy tissues. Nonetheless, accuracy in the determination of the dose distribution in proton-therapy is up to now limited by the uncertainty in stopping powers, which are presently calculated from the photon attenuation coefficients measured by X-ray tomography. Proton computed tomography apparatus (pCT) has been proposed to directly measure the stopping power and reduce this uncertainty. Main problem with proton imaging is the blurring effect introduced by multiple Coulomb scattering: single proton tracking is a promising technique to face this difficulty. As a first step towards a pCT system, we designed a proton radiography (pCR) prototype based on a silicon microstrip tracker (to characterize particle trajectories) and a segmented YAG:Ce calorimeter (to measure their residual energy). Aim of the system is to detect protons with a 1 MHz particle rate of and with kinetic energy in the range 250–270 MeV, high enough to pass through human body. Design and development of the pCR prototype, as well as the characterization of its single components, are described in this paper.
2010
Volume: 57 Issue: 1 Part 1
8
16
D.Menichelli; M.Bruzzi; M.Bucciolini; G.Candiano; G.A.P.Cirrone; L. Capineri; C.Civinini; G.Cuttone; D.Lo Presti; L. Marrazzo; S. Pallotta; N.Randazzo; V.Sipala; C.Talamonti ; S.Valentini; S.Pieri; V.Reggioli; M.Brianzi; M.Tesi
File in questo prodotto:
File Dimensione Formato  
paper1.pdf

Accesso chiuso

Tipologia: Versione finale referata (Postprint, Accepted manuscript)
Licenza: Tutti i diritti riservati
Dimensione 854.48 kB
Formato Adobe PDF
854.48 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/362593
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 31
  • ???jsp.display-item.citation.isi??? 26
social impact