Fifty patients with rheumatoid arthritis (RA) were studied to find a possible correlation between some humoral parameters, considered as indexes of the active inflammation, and serum gamma-glutamyl transpeptidase (GGTP); 31 patients with osteoarthrosis were examined as controls. The low coefficient of correlation, obtained in subjects with RA, between GGTP and CRP, alpha 1-acid glycoprotein, fibrinogen and ESR (p less than 0.05) seems to indicate that measurement of this enzyme is of little practical value as an index of the activity of RA. Furthermore, the resulting correlations between serum GGTP and other liver function tests in relation to anti-inflammatory and sedative therapy in patients with RA are considered.

Critical evaluation of gamma-glutamyl transpeptidase levels in rheumatoid arthritis and laboratory indices of disease activity / Bianucci G;Pinto S;Maddali Bongi S;Saullo S.. - In: LA RICERCA IN CLINICA E IN LABORATORIO. - ISSN 0390-5748. - STAMPA. - 11:(1981), pp. 159-168.

Critical evaluation of gamma-glutamyl transpeptidase levels in rheumatoid arthritis and laboratory indices of disease activity

MADDALI BONGI, SUSANNA;
1981

Abstract

Fifty patients with rheumatoid arthritis (RA) were studied to find a possible correlation between some humoral parameters, considered as indexes of the active inflammation, and serum gamma-glutamyl transpeptidase (GGTP); 31 patients with osteoarthrosis were examined as controls. The low coefficient of correlation, obtained in subjects with RA, between GGTP and CRP, alpha 1-acid glycoprotein, fibrinogen and ESR (p less than 0.05) seems to indicate that measurement of this enzyme is of little practical value as an index of the activity of RA. Furthermore, the resulting correlations between serum GGTP and other liver function tests in relation to anti-inflammatory and sedative therapy in patients with RA are considered.
1981
11
159
168
Bianucci G;Pinto S;Maddali Bongi S;Saullo S.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/717129
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