The sulfonamide moiety is a common pharmacophore in many biologically active compounds, such as HIV inhibitors, antimicrobial drugs, carbonic anhydrase inhibitors and anti-tumor agents. Because the structural and conformational properties of a compound usually are related to its biological properties, their study would provide useful information to design new effective drugs.
N,N-Diethyl-2-(4-methylbenzenesulfonamido)benzamide / M. Altamura; V. Fedi; R. Nannicini; P. Paoli; P. Rossi. - In: ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE. - ISSN 1600-5368. - ELETTRONICO. - E68:(2012), pp. o3144-o3145. [10.1107/S160053681204264X]
N,N-Diethyl-2-(4-methylbenzenesulfonamido)benzamide
PAOLI, PAOLA;ROSSI, PATRIZIA
2012
Abstract
The sulfonamide moiety is a common pharmacophore in many biologically active compounds, such as HIV inhibitors, antimicrobial drugs, carbonic anhydrase inhibitors and anti-tumor agents. Because the structural and conformational properties of a compound usually are related to its biological properties, their study would provide useful information to design new effective drugs.
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