FLG 29.1 cells, cultured at 1xg, are able to switch on a differentiating process only when they are suitably induced by chemical factors. On the contrary, when FLG 29.1 cells are cultured in conditions of gravitational unloading, simulated by a Random Positioning Machine, the switching on of the differentiation process occurs in the absence of any added differentiating agent or any stimulating factor. The phenotypic characterization of the cells and quantitative measures of their bone resorption activity are consistent with a differentiation process through the osteoclastic pathway.
Gravitational unloading induces osteoclast-like diffrenetiation of FLG 29.1 cells / Monici M; Agati G; Fusi F; Paglierani M; Cogoli A; Bernabei PA. - In: JOURNAL OF GRAVITATIONAL PHYSIOLOGY. - ISSN 1077-9248. - STAMPA. - 9:(2002), pp. 261-262.
Gravitational unloading induces osteoclast-like diffrenetiation of FLG 29.1 cells
MONICI, MONICA;FUSI, FRANCO;
2002
Abstract
FLG 29.1 cells, cultured at 1xg, are able to switch on a differentiating process only when they are suitably induced by chemical factors. On the contrary, when FLG 29.1 cells are cultured in conditions of gravitational unloading, simulated by a Random Positioning Machine, the switching on of the differentiation process occurs in the absence of any added differentiating agent or any stimulating factor. The phenotypic characterization of the cells and quantitative measures of their bone resorption activity are consistent with a differentiation process through the osteoclastic pathway.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.