Relaxin has been reported to influence gastrointestinal motility in mice. However, at present, nothing is known about the effects of relaxin on the electrophysiological properties of the gastrointestinal smooth muscle. In the present experiments relaxin, other than influencing the colonic motility pattern, has been shown to act on cell membrane properties. The results of the present study indicate that relaxin directly modulates the motility of the proximal colon and the membrane potential of smooth muscle.
Muscular effects of relaxin on the mouse colon: mechanical and electrophysiological studies / R. Squecco; R. Garella; F. Francini; M.C. Baccari. - In: ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY. - ISSN 1122-6714. - ELETTRONICO. - 118:(2013), pp. 82-83. (Intervento presentato al convegno 6th International conference on relaxin and related peptides).
Muscular effects of relaxin on the mouse colon: mechanical and electrophysiological studies
SQUECCO, ROBERTA;GARELLA, RACHELE;FRANCINI, FABIO;BACCARI, MARIA CATERINA
2013
Abstract
Relaxin has been reported to influence gastrointestinal motility in mice. However, at present, nothing is known about the effects of relaxin on the electrophysiological properties of the gastrointestinal smooth muscle. In the present experiments relaxin, other than influencing the colonic motility pattern, has been shown to act on cell membrane properties. The results of the present study indicate that relaxin directly modulates the motility of the proximal colon and the membrane potential of smooth muscle.File | Dimensione | Formato | |
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