An up-to-date overview of thin-layer chromatography (TLC) techniques for chiral separations of various signi fi cant and/or recent examples of enantioresolutions is reported. Furthermore, examples for chiral separations obtained on achiral commercially available C18 TLC plates are described in detail. These include the enantioseparation of methylthiohydantoin-phenylalanine and methylthiohydantoin-tyrosine using hydroxyethyl- b -cyclodextrin as mobile phase additive and the separation of the enantiomers of warfarin and p -chlorowarfarin using bovine serum albumin as mobile phase additive.

Enantioseparations by Thin-Layer Chromatography / Massimo Del Bubba;Leonardo Checchini;Alessandra Cincinelli;Luciano Lepri. - STAMPA. - (2013), pp. 29-43. [10.1007/978-1-62703-263-6_2]

Enantioseparations by Thin-Layer Chromatography

DEL BUBBA, MASSIMO;CHECCHINI, LEONARDO;CINCINELLI, ALESSANDRA;LEPRI, LUCIANO
2013

Abstract

An up-to-date overview of thin-layer chromatography (TLC) techniques for chiral separations of various signi fi cant and/or recent examples of enantioresolutions is reported. Furthermore, examples for chiral separations obtained on achiral commercially available C18 TLC plates are described in detail. These include the enantioseparation of methylthiohydantoin-phenylalanine and methylthiohydantoin-tyrosine using hydroxyethyl- b -cyclodextrin as mobile phase additive and the separation of the enantiomers of warfarin and p -chlorowarfarin using bovine serum albumin as mobile phase additive.
2013
9781627032629
9781627032636
Chiral Separations - Methods and protocols
29
43
Massimo Del Bubba;Leonardo Checchini;Alessandra Cincinelli;Luciano Lepri
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/823278
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