Sfoglia per Autore
Secreted sphingosine 1-phosphate exerts a novel autocrine action in bone marrow-derived mesenchymal stromal cell signalling
2016 Pierucci, F; Sassoli, C; Tani, A; Frati, A; Bigi, A; Chellini, F; Matteini, F; Anderloni, G; Nosi, D; Mazzanti, B; Zecchi-Orlandini, S; Meacci, E
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload
2017 Cascella, Roberta; Evangelisti, Elisa; Bigi, Alessandra; Becatti, Matteo; Fiorillo, Claudia; Stefani, Massimo; Chiti, Fabrizio; Cecchi, Cristina
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain
2019 La Manna, Sara; Scognamiglio, Pasqualina; Roviello, Valentina; Borbone, Fabio; Florio, Daniele; Di Natale, Concetta ; Bigi, Alessandra; Cecchi, Cristina; Cascella, Roberta; Giannini, Cinzia; Sibillano, Teresa; Novellino, Ettore; Marasco, Daniela
TRAFAIR: Understanding traffic flow to improve air quality
2019 Po L.; Rollo F.; Viqueira J.R.R.; Lado R.T.; Bigi A.; Lopez J.C.; Paolucci M.; Nesi P.
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases
2019 Cascella R, Fani G, Bigi A, Chiti F, Cecchi C.
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation
2019 Hassan Ramshini , Reza Tayebee, Alessandra Bigi, Francesco Bemporad, Cristina Cecchi, Fabrizio Chiti
Study of the relationship between structure and toxicity of different α-synuclein aggregates and related cellular dysfunctions
2020 Alessandra Bigi
Targeting pathological amyloid aggregates with conformation-sensitive antibodies
2020 Alessandra Bigi, Gilda Loffredo, Roberta Cascella, Cristina Cecchi
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism
2020 Ryan Limbocker, Benedetta Mannini, Francesco S. Ruggeri, Roberta Cascella, Catherine K. Xu, Michele Perni, Sean Chia, Serene W. Chen, Johnny Habchi, Alessandra Bigi, Ryan P. Kreiser, Aidan K. Wright, J. Alex Albright, Tadas Kartanas, Janet R. Kumita, Nunilo Cremades, Michael Zasloff, Cristina Cecchi, Tuomas P. J. Knowles, Fabrizio Chiti, Michele Vendruscolo, Christopher M. Dobson
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells
2021 Roberta Cascella, Serene W Chen , Alessandra Bigi, José D Camino, Catherine K Xu, Christopher M Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy
2021 Bigi A.; Ermini E.; Chen S.W.; Cascella R.; Cecchi C.
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers
2021 Ryan Limbocker, Roxine Staats, Sean Chia, Francesco S Ruggeri, Benedetta Mannini, Catherine K Xu, Michele Perni, Roberta Cascella, Alessandra Bigi, Liam R Sasser, Natalie R Block, Aidan K Wright, Ryan P Kreiser, Edward T Custy, Georg Meisl, Silvia Errico, Johnny Habchi, Patrick Flagmeier, Tadas Kartanas, Jared E Hollows, Lam T Nguyen, Kathleen LeForte, Denise Barbut, Janet R Kumita, Cristina Cecchi, Michael Zasloff, Tuomas P J Knowles, Christopher M Dobson, Fabrizio Chiti, Michele Vendruscolo
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases
2022 Alessandra Bigi, Roberta Cascella, Fabrizio Chiti, Cristina Cecchi
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43
2022 Roberta Cascella, Alessandra Bigi, Dylan Giorgino Riffert, Maria Cristina Gagliani, Emilio Ermini, Matteo Moretti, Katia Cortese, Cristina Cecchi, Fabrizio Chiti
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation.
2022 Tommaso Staderini, Alessandra Bigi, Daniele Mongiello, Cristina Cecchi, Fabrizio Chiti
Biophysical characterization of full length TAR DNA-Binding Protein (TDP-43) phase separation
2022 Tommaso Staderini, Alessandra Bigi, Daniele Mongiello, Cristina Cecchi, Fabrizio Chiti
Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies
2022 Roberta Cascella, Alessandra Bigi, Nunilo Cremades, Cristina Cecchi
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature
2023 Cascella R, Banchelli M, Abolghasem Ghadami S, Ami D, Gagliani MC, Bigi A, Staderini T, Tampellini D, Cortese K, Cecchi C, Natalello A, Adibi H, Matteini P, Chiti F.
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature
2023 Roberta Cascella, Martina Banchelli, Seyyed Abolghasem Ghadami, Diletta Ami, Maria Cristina Gagliani, Alessandra Bigi, Tommaso Staderini, Davide Tampellini, Katia Cortese, Cristina Cecchi, Antonino Natalello, Hadi Adibi, Paolo Matteini, Fabrizio Chiti
α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies
2023 Alessandra Bigi, Roberta Cascella, Cristina Cecchi
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Secreted sphingosine 1-phosphate exerts a novel autocrine action in bone marrow-derived mesenchymal stromal cell signalling | 2016 | Pierucci, F; Sassoli, C; Tani, A; Frati, A; Bigi, A; Chellini, F; Matteini, F; Anderloni, G; Nosi, D; Mazzanti, B; Zecchi-Orlandini, S; Meacci, E | |
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload | 2017 | Cascella, Roberta; Evangelisti, Elisa; Bigi, Alessandra; Becatti, Matteo; Fiorillo, Claudia; Stefani, Massimo; Chiti, Fabrizio; Cecchi, Cristina | |
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain | 2019 | La Manna, Sara; Scognamiglio, Pasqualina; Roviello, Valentina; Borbone, Fabio; Florio, Daniele; Di Natale, Concetta ; Bigi, Alessandra; Cecchi, Cristina; Cascella, Roberta; Giannini, Cinzia; Sibillano, Teresa; Novellino, Ettore; Marasco, Daniela | |
TRAFAIR: Understanding traffic flow to improve air quality | 2019 | Po L.; Rollo F.; Viqueira J.R.R.; Lado R.T.; Bigi A.; Lopez J.C.; Paolucci M.; Nesi P. | |
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases | 2019 | Cascella R, Fani G, Bigi A, Chiti F, Cecchi C. | |
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation | 2019 | Hassan Ramshini , Reza Tayebee, Alessandra Bigi, Francesco Bemporad, Cristina Cecchi, Fabrizio Chiti | |
Study of the relationship between structure and toxicity of different α-synuclein aggregates and related cellular dysfunctions | 2020 | Alessandra Bigi | |
Targeting pathological amyloid aggregates with conformation-sensitive antibodies | 2020 | Alessandra Bigi, Gilda Loffredo, Roberta Cascella, Cristina Cecchi | |
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism | 2020 | Ryan Limbocker, Benedetta Mannini, Francesco S. Ruggeri, Roberta Cascella, Catherine K. Xu, Michele Perni, Sean Chia, Serene W. Chen, Johnny Habchi, Alessandra Bigi, Ryan P. Kreiser, Aidan K. Wright, J. Alex Albright, Tadas Kartanas, Janet R. Kumita, Nunilo Cremades, Michael Zasloff, Cristina Cecchi, Tuomas P. J. Knowles, Fabrizio Chiti, Michele Vendruscolo, Christopher M. Dobson | |
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells | 2021 | Roberta Cascella, Serene W Chen , Alessandra Bigi, José D Camino, Catherine K Xu, Christopher M Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi | |
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy | 2021 | Bigi A.; Ermini E.; Chen S.W.; Cascella R.; Cecchi C. | |
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers | 2021 | Ryan Limbocker, Roxine Staats, Sean Chia, Francesco S Ruggeri, Benedetta Mannini, Catherine K Xu, Michele Perni, Roberta Cascella, Alessandra Bigi, Liam R Sasser, Natalie R Block, Aidan K Wright, Ryan P Kreiser, Edward T Custy, Georg Meisl, Silvia Errico, Johnny Habchi, Patrick Flagmeier, Tadas Kartanas, Jared E Hollows, Lam T Nguyen, Kathleen LeForte, Denise Barbut, Janet R Kumita, Cristina Cecchi, Michael Zasloff, Tuomas P J Knowles, Christopher M Dobson, Fabrizio Chiti, Michele Vendruscolo | |
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases | 2022 | Alessandra Bigi, Roberta Cascella, Fabrizio Chiti, Cristina Cecchi | |
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 | 2022 | Roberta Cascella, Alessandra Bigi, Dylan Giorgino Riffert, Maria Cristina Gagliani, Emilio Ermini, Matteo Moretti, Katia Cortese, Cristina Cecchi, Fabrizio Chiti | |
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation. | 2022 | Tommaso Staderini, Alessandra Bigi, Daniele Mongiello, Cristina Cecchi, Fabrizio Chiti | |
Biophysical characterization of full length TAR DNA-Binding Protein (TDP-43) phase separation | 2022 | Tommaso Staderini, Alessandra Bigi, Daniele Mongiello, Cristina Cecchi, Fabrizio Chiti | |
Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies | 2022 | Roberta Cascella, Alessandra Bigi, Nunilo Cremades, Cristina Cecchi | |
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature | 2023 | Cascella R, Banchelli M, Abolghasem Ghadami S, Ami D, Gagliani MC, Bigi A, Staderini T, Tampellini D, Cortese K, Cecchi C, Natalello A, Adibi H, Matteini P, Chiti F. | |
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature | 2023 | Roberta Cascella, Martina Banchelli, Seyyed Abolghasem Ghadami, Diletta Ami, Maria Cristina Gagliani, Alessandra Bigi, Tommaso Staderini, Davide Tampellini, Katia Cortese, Cristina Cecchi, Antonino Natalello, Hadi Adibi, Paolo Matteini, Fabrizio Chiti | |
α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies | 2023 | Alessandra Bigi, Roberta Cascella, Cristina Cecchi |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile