Sfoglia per Autore
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.
2005 H. Turkmen;M. Durgun;S. Yilmaztekin;M. Emul;A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.
2005 L. Puccetti;G. Fasolis;D. Vullo;Z. H. Chohan;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
2005 F. Mincione;M. Starnotti;E. Masini;L. Bacciottini;C. Scrivanti;A. Casini;D. Vullo;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.
2005 I. Nishimori;D. Vullo;A. Innocenti;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran
Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides.
2005 S. Pastorekova;D. Vullo;A. Casini;A. Scozzafava;J. Pastorek;I. Nishimori;C. T. Supuran
Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.
2005 I. Nishimori;D. Vullo;A. Innocenti;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran
Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.
2005 A. Cecchi;S. D. Taylor;Y. Liu;B. Hill;D. Vullo;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides.
2005 A. Innocenti;R. Villar;V. Martinez-Merino;M. J. Gil;A. Scozzafava;D. Vullo;C. T. Supuran
Carbonic anhydrase inhibitors: inhibition of the human transmembrane isozyme XIV with a library of aromatic/heterocyclic sulfonamides.
2005 O. Ozensoy;I. Nishimori;D. Vullo;L. Puccetti;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?
2005 D. Vullo;A. Innocenti;I. Nishimori;J. Pastorek;A. Scozzafava;S. Pastoreková;C. T. Supuran
Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.
2005 V. Garaj;L. Puccetti;G. Fasolis;J. Winum;J. Montero;A. Scozzafava;D. Vullo;A. Innocenti;C. T. Supuran
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.
2005 D. Vullo;J. Voipio;A. Innocenti;C. Rivera;H. Ranki;A. Scozzafava;K. Kaila;C. T. Supuran
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.
2005 J. Winum;S. Pastorekova;L. Jakubickova;J. Montero;A. Scozzafava;J. Pastorek;D. Vullo;A. Innocenti;C. T. Supuran
Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.
2006 J. Winum;C. Temperini;K. E. Cheikh;A. Innocenti;D. Vullo;S. Ciattini;J. Montero;A. Scozzafava;C. T. Supuran
Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.
2006 S. Parkkila;D. Vullo;L. Puccetti;A. Parkkila;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors: inhibition of the cytosolic human isozyme VII with anions.
2006 D. Vullo;E. Ruusuvuori;K. Kaila;A. Scozzafava;C. T. Supuran
Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design.
2006 C. Temperini;A. Scozzafava;D. Vullo;C. T. Supuran
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.
2006 I. Nishimori;D. Vullo;T. Minakuchi;K. Morimoto;S. Onishi;A. Scozzafava;C. T. Supuran
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.
2006 I. Nishimori;T. Minakuchi;K. Morimoto;S. Sano;S. Onishi;H. Takeuchi;D. Vullo;A. Scozzafava;C. T. Supuran
Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.
2006 C. Temperini;A. Scozzafava;D. Vullo;C. T. Supuran
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