CASCELLA, ROBERTA

CASCELLA, ROBERTA  

Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'  

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Risultati 1 - 20 di 67 (tempo di esecuzione: 0.033 secondi).
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A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 2011 Zampagni M; Cascella R; Casamenti F; Grossi C; Evangelisti E; Wright D; Becatti M; Liguri G; Mannini B; Campioni S; Chiti F; Cecchi C.
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 2017 Perni, Michele; Galvagnion, Céline; Maltsev, Alexander; Meisl, Georg; Müller, Martin B. D.; Challa, Pavan K.; Kirkegaard, Julius B.; Flagmeier, Patrick; Cohen, Samuel I. A.; Cascella, Roberta; Chen, Serene W.; Limboker, Ryan; Sormanni, Pietro; Heller, Gabriella T.; Aprile, Francesco A.; Cremades, Nunilo; Cecchi, Cristina; Chiti, Fabrizio; Nollen, Ellen A. A.; Knowles, Tuomas P. J.; Vendruscolo, Michele; Bax, Adriaan; Zasloff, Michael; M. Dobson, Christopher
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 2022 Roberta Cascella, Alessandra Bigi, Dylan Giorgino Riffert, Maria Cristina Gagliani, Emilio Ermini, Matteo Moretti, Katia Cortese, Cristina Cecchi, Fabrizio Chiti
A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer's disease CSF 2024 Alessandra Bigi, Liliana Napolitano, Devkee M. Vadukul, Fabrizio Chiti, Cristina Cecchi, Francesco A. Aprile, Roberta Cascella
Allele specific Taqman–based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients. 2010 Pinzani P; Salvianti F; Cascella R; Massi D; De Giorgi V; Pazzagli M; Orlando C.
Amyloid cytotoxicity depends on membrane lipid composition in Alzheimer's disease 2014 Nacmias B.; Evangelisti E.; Cascella R.; Bagnoli S.; Sorbi S.; Cecchi C.
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 2022 Alessandra Bigi, Roberta Cascella, Fabrizio Chiti, Cristina Cecchi
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 2023 Cascella R, Banchelli M, Abolghasem Ghadami S, Ami D, Gagliani MC, Bigi A, Staderini T, Tampellini D, Cortese K, Cecchi C, Natalello A, Adibi H, Matteini P, Chiti F.
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 2023 Roberta Cascella, Martina Banchelli, Seyyed Abolghasem Ghadami, Diletta Ami, Maria Cristina Gagliani, Alessandra Bigi, Tommaso Staderini, Davide Tampellini, Katia Cortese, Cristina Cecchi, Antonino Natalello, Hadi Adibi, Paolo Matteini, Fabrizio Chiti
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility 2023 Claudia Capitini, Alessandra Bigi, Niccolò Parenti, Marco Emanuele, Niccolò Bianchi, Roberta Cascella, Cristina Cecchi, Laura Maggi, Francesco Annunziato, Francesco Saverio Pavone, Martino Calamai
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 2021 Giulia Fani, Benedetta Mannini, Giulia Vecchi, Roberta Cascella, Cristina Cecchi, Christopher M. Dobson, Michele Vendruscolo, Fabrizio Chiti
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 2016 Evangelisti, Elisa; Cascella, Roberta; Becatti, Matteo; Marrazza, Giovanna; Dobson, Christopher M.; Chiti, Fabrizio; Stefani, Massimo; Cecchi, Cristina
Calcium dyshomeostasis in Alzheimer’s disease pathogenesis 2021 Cascella R.; Cecchi C.
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 2011 B. Mannini; S. Campioni; M. Boninsegna; E. Palagano; R. Cascella; M. Zampagni; A. Penco; M. Wilson; S. Meehan; C. Roodveldt; A. Relini; C. Cecchi; F. Chiti
Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action 2012 B. Mannini; S. Campioni; M. Boninsegna; A. Penco; R. Cascella; M. Zampagni; M. Wilson; S. Meehan; C. Roodveldt; C. Dobson; A. Relini; C. Cecchi; F. Chiti
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 2016 Pasqualina Liana Scognamiglio; Concetta Di Natale; Marilisa Leone; Roberta Cascella; Cristina Cecchi; Lisa Lirussi; Giulia Antoniali; Domenico Riccardi; Giancarlo Morelli; Gianluca Tell; Fabrizio Chiti; Daniela Marasco
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 2016 Cappelli, S; Penco, A; Mannini, Benedetta; Cascella, Roberta; Wilson, M; Ecroyd, H; Li, X; Buxbaum, J; Dobson, Cm; Cecchi, Cristina; Relini, A; Chiti, Fabrizio
Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies 2022 Roberta Cascella, Alessandra Bigi, Nunilo Cremades, Cristina Cecchi
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy 2021 Bigi A.; Ermini E.; Chen S.W.; Cascella R.; Cecchi C.
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 2013 Roberta Cascella; Simona Conti; Francesca Tatini; Elisa Evangelisti; Tania Scartabelli; Fiorella Casamenti; Mark R. Wilson; Fabrizio Chiti; Cristina Cecchi.