SQUARCIALUPI, LUCIA
SQUARCIALUPI, LUCIA
Scienze della Salute (DSS)
1,2,4-Benzothiadiazine-1,1-dioxide Derivatives as Ionotropic Glutamate Receptor Ligands: Synthesis and Structure–Activity Relationships
2014 Flavia Varano; Daniela Catarzi; Vittoria Colotta; Lucia Squarcialupi; Rosanna Matucci
1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies
2015 Daniela Catarzi ; Flavia Varano; Daniela Poli ; Lucia Squarcialupi; Marco Betti ; Letizia Trincavelli; Claudia Martini ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta
1,2,4-Triazolo[4,3-a]pyrazin-3-one as a new scaffold to develop potent adenosine receptor antagonists
2014 V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; R. Volpini; M. Buccioni; D. Dal Ben.
2-Arylimidazo[1,2-a]pyrazin-8-amino derivatives as high-affinity fluorescent human A3 adenosine receptor antagonists with potential neuroprotective properties
2013 D. Catarzi; V. Colotta; F. Varano; L. Squarcialupi; K. Varani; A.M. Pugliese; F. Pedata; I. Palchetti
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino Derivatives As New Potent and Selective Human A3Adenosine Receptor Antagonists. Molecular Modeling Studies and Pharmacological Evaluation
2013 Lucia Squarcialupi;Vittoria Colotta;Daniela Catarzi;Flavia Varano;Guido Filacchioni;Katia Varani;Carmen Corciulo;Fabrizio Vincenzi;Pier Andrea Borea;Carla Ghelardini;Lorenzo Di Cesare Mannelli;Antonella Ciancetta;Stefano Moro
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives, new potent and selective human A3 adenosine receptor antagonists endowed with protective effect against oxaliplatin-induced apoptosis in rat astrocyte cell cultures
2012 V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; M. Zanardelli; L. Di Cesare Mannelli; C. Ghelardini; S. Paoletta; S. Moro
2-Hydroxy-1,2,4-benzothiadiazin-1,1-dioxide derivatives as new antagonists of ionotropic glutamate receptors
2013 F. Varano; D. Catarzi; V. Colotta; L. Squarcialupi; R. Matucci.
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII
2017 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studies.
2012 Colotta V;Lenzi O;Catarzi D;Varano F;Squarcialupi L;Costagli C;Galli A;Ghelardini C;Pugliese AM;Maraula G;Coppi E;Pellegrini-Giampietro DE;Pedata F;Sabbadin D;Moro S
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII.
2015 Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V.
4-Alkyloxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y6 receptor
2013 P. Suresh Jayasekara; Matthew O. Barrett; Christopher B. Ball; Kyle A. Brown; Eszter Kozma; Stefano Costanzi; Lucia Squarcialupi; Ramachandran Balasubramanian; Hiroshi Maruoka and Kenneth A. Jacobson
7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: Structural investigations at the 5-position to target human A1 and A2A adenosine receptors. Molecular modeling and pharmacological studies
2014 Lucia Squarcialupi; Vittoria Colotta; Daniela Catarzi; Flavia Varano; Betti Marco; Katia Varani; Fabrizio Vincenzi; Pier Andrea Borea; Nicola Porta; Antonella Ciancetta; Stefano Moro
A comprehensive strategy in the development of a cyclodextrin-modified microemulsion electrokinetic chromatographic method for the assay of diclofenac and its impurities: Mixture-process variable experiments and quality by design
2016 Orlandini, S.; Pasquini, B.; Caprini, C.; Del Bubba, M.; Squarcialupi, L.; Colotta, V.; Furlanetto, S.
Arilpirazolo[4,3-d]pirimidin-7-ammino derivati quali nuovi antagonisti potenti e selettivi del recettore umano A3 dell’adenosina
2013 L. Squarcialupi; V. Colotta; D. Catarzi; F. Varano; K. Varani; C. Corciulo; F. Vincenzi; A. Ciancetta; L. Di Cesare Mannelli; C. Ghelardini; S. Moro
Characterization by flow cytometry of fluorescent, selective agonist probes of the A3 adenosine receptor
2013 Eszter Kozma ; Elizabeth T. Gizewski ; Dilip K. Tosh ; Lucia Squarcialupi ; John A. Auchampach ; Kenneth A. Jacobson
Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation
2015 Flavia Varano; Daniela Catarzi ; Lucia Squarcialupi ; Marco Betti ; Fabrizio Vincenzi ; Annalisa Ravani ; Katia Varani ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta
Exploring the effect of 2- and 5-substituents on the pyrazolo[4,3-d]pyrimidin-7-amino derivatives to obtain human adenosine receptor antagonists
2013 V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; A. Ciancetta; S. Moro
Fluorescent ligands for adenosine receptors
2012 Eszter Kozma; P. Suresh Jayasekara; Lucia Squarcialupi; Silvia Paoletta; Stefano Moro; Stephanie Federico; Giampiero Spalluto; Kenneth A. Jacobson
Imidazo[1,2-a]pyrazine core for the design of new adenosine receptor antagonist: optimization of A3 affinity and structural exploration to target the A2A subtype
2014 D. Catarzi; V. Colotta; F. Varano; L. Squarcialupi; K. Varani
New 5-heteroaryl-pyrazolo[4,3-d]pyrimidin-7-amines as dual human adenosine A1 and A2A receptor antagonists.
2016 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Lambertucci, Catia; Volpini, Rosaria; Colotta, Vittoria
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,4-Benzothiadiazine-1,1-dioxide Derivatives as Ionotropic Glutamate Receptor Ligands: Synthesis and Structure–Activity Relationships | 2014 | Flavia Varano; Daniela Catarzi; Vittoria Colotta; Lucia Squarcialupi; Rosanna Matucci | |
| 1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies | 2015 | Daniela Catarzi ; Flavia Varano; Daniela Poli ; Lucia Squarcialupi; Marco Betti ; Letizia Trincavelli; Claudia Martini ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta | |
| 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a new scaffold to develop potent adenosine receptor antagonists | 2014 | V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; R. Volpini; M. Buccioni; D. Dal Ben. | |
| 2-Arylimidazo[1,2-a]pyrazin-8-amino derivatives as high-affinity fluorescent human A3 adenosine receptor antagonists with potential neuroprotective properties | 2013 | D. Catarzi; V. Colotta; F. Varano; L. Squarcialupi; K. Varani; A.M. Pugliese; F. Pedata; I. Palchetti | |
| 2-Arylpyrazolo[4,3-d]pyrimidin-7-amino Derivatives As New Potent and Selective Human A3Adenosine Receptor Antagonists. Molecular Modeling Studies and Pharmacological Evaluation | 2013 | Lucia Squarcialupi;Vittoria Colotta;Daniela Catarzi;Flavia Varano;Guido Filacchioni;Katia Varani;Carmen Corciulo;Fabrizio Vincenzi;Pier Andrea Borea;Carla Ghelardini;Lorenzo Di Cesare Mannelli;Antonella Ciancetta;Stefano Moro | |
| 2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives, new potent and selective human A3 adenosine receptor antagonists endowed with protective effect against oxaliplatin-induced apoptosis in rat astrocyte cell cultures | 2012 | V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; M. Zanardelli; L. Di Cesare Mannelli; C. Ghelardini; S. Paoletta; S. Moro | |
| 2-Hydroxy-1,2,4-benzothiadiazin-1,1-dioxide derivatives as new antagonists of ionotropic glutamate receptors | 2013 | F. Varano; D. Catarzi; V. Colotta; L. Squarcialupi; R. Matucci. | |
| 3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII | 2017 | Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria | |
| 3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studies. | 2012 | Colotta V;Lenzi O;Catarzi D;Varano F;Squarcialupi L;Costagli C;Galli A;Ghelardini C;Pugliese AM;Maraula G;Coppi E;Pellegrini-Giampietro DE;Pedata F;Sabbadin D;Moro S | |
| 3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII. | 2015 | Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V. | |
| 4-Alkyloxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y6 receptor | 2013 | P. Suresh Jayasekara; Matthew O. Barrett; Christopher B. Ball; Kyle A. Brown; Eszter Kozma; Stefano Costanzi; Lucia Squarcialupi; Ramachandran Balasubramanian; Hiroshi Maruoka and Kenneth A. Jacobson | |
| 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: Structural investigations at the 5-position to target human A1 and A2A adenosine receptors. Molecular modeling and pharmacological studies | 2014 | Lucia Squarcialupi; Vittoria Colotta; Daniela Catarzi; Flavia Varano; Betti Marco; Katia Varani; Fabrizio Vincenzi; Pier Andrea Borea; Nicola Porta; Antonella Ciancetta; Stefano Moro | |
| A comprehensive strategy in the development of a cyclodextrin-modified microemulsion electrokinetic chromatographic method for the assay of diclofenac and its impurities: Mixture-process variable experiments and quality by design | 2016 | Orlandini, S.; Pasquini, B.; Caprini, C.; Del Bubba, M.; Squarcialupi, L.; Colotta, V.; Furlanetto, S. | |
| Arilpirazolo[4,3-d]pirimidin-7-ammino derivati quali nuovi antagonisti potenti e selettivi del recettore umano A3 dell’adenosina | 2013 | L. Squarcialupi; V. Colotta; D. Catarzi; F. Varano; K. Varani; C. Corciulo; F. Vincenzi; A. Ciancetta; L. Di Cesare Mannelli; C. Ghelardini; S. Moro | |
| Characterization by flow cytometry of fluorescent, selective agonist probes of the A3 adenosine receptor | 2013 | Eszter Kozma ; Elizabeth T. Gizewski ; Dilip K. Tosh ; Lucia Squarcialupi ; John A. Auchampach ; Kenneth A. Jacobson | |
| Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation | 2015 | Flavia Varano; Daniela Catarzi ; Lucia Squarcialupi ; Marco Betti ; Fabrizio Vincenzi ; Annalisa Ravani ; Katia Varani ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta | |
| Exploring the effect of 2- and 5-substituents on the pyrazolo[4,3-d]pyrimidin-7-amino derivatives to obtain human adenosine receptor antagonists | 2013 | V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; A. Ciancetta; S. Moro | |
| Fluorescent ligands for adenosine receptors | 2012 | Eszter Kozma; P. Suresh Jayasekara; Lucia Squarcialupi; Silvia Paoletta; Stefano Moro; Stephanie Federico; Giampiero Spalluto; Kenneth A. Jacobson | |
| Imidazo[1,2-a]pyrazine core for the design of new adenosine receptor antagonist: optimization of A3 affinity and structural exploration to target the A2A subtype | 2014 | D. Catarzi; V. Colotta; F. Varano; L. Squarcialupi; K. Varani | |
| New 5-heteroaryl-pyrazolo[4,3-d]pyrimidin-7-amines as dual human adenosine A1 and A2A receptor antagonists. | 2016 | Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Varani, Katia; Vincenzi, Fabrizio; Ben, Diego Dal; Lambertucci, Catia; Volpini, Rosaria; Colotta, Vittoria |