VARANO, FLAVIA

VARANO, FLAVIA  

Neuroscienze, Area del Farmaco e Salute del Bambino (NEUROFARBA)  

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Titolo Data di pubblicazione Autore(i) File
1,2,4-Benzothiadiazine-1,1-dioxide Derivatives as Ionotropic Glutamate Receptor Ligands: Synthesis and Structure–Activity Relationships 2014 Flavia Varano; Daniela Catarzi; Vittoria Colotta; Lucia Squarcialupi; Rosanna Matucci
1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives. 2005 D. CATARZI; V. COLOTTA; F. VARANO; O. LENZI; G. FILACCHIONI; L. TRINCAVELLI; C. MARTINI; C. MONOPOLI; S. MORO
1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies 2015 Daniela Catarzi ; Flavia Varano; Daniela Poli ; Lucia Squarcialupi; Marco Betti ; Letizia Trincavelli; Claudia Martini ; Diego Dal Ben ; Ajiroghene Thomas ; Rosaria Volpini ; Vittoria Colotta
“1,2,4-TRIAZOLO[1,5-A]QUINOXALINE DERIVATIVES: SYNTHESIS AND BIOLOGICAL EVALUATION AS ADENOSINE RECEPTOR ANTAGONISTS” 2004 D. CATARZI; V. COLOTTA; F. VARANO; G.FILACCHIONI; C. MARTINI; L. TRINCAVELLI; A. LUCACCHINI
1,2,4-Triazolo[4,3-a]pyrazin-3-one as a new scaffold to develop potent adenosine receptor antagonists 2014 V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; R. Volpini; M. Buccioni; D. Dal Ben.
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 2017 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Dal Ben, Diego; Marucci, Gabriella; Buccioni, Michela; Volpini, Rosaria; De Vita, Teresa; Cavalli, Andrea; Colotta, Vittoria
1,2,4-triazolo[4,3-a]quinoxalin-1-one as a framework to obtain potent and selective A1, A2A and A3 adenosine receptor antagonists 1999 Vittoria Colotta; Daniela Catarzi; Flavia Varano; Letizia Trincavelli
The 1,2,4-Triazolo[4,3-a]quinoxalin-1-one Moiety as an Attractive Scaffold to Develop New Potent and Selective Human A3 Adenosine Receptor Antagonists: Synthesis, Pharmacological and Ligand-Receptor Modeling Studies. 2004 V. COLOTTA; D. CATARZI; F.VARANO; F. R. CALABRI; O. LENZI; G. FILACCHIONI; C. MARTINI; L. TRINCAVELLI; FRANCESCA DEFLORIAN; STEFANO MORO
1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists. 2000 V. COLOTTA; D. CATARZI; F. VARANO; L.CECCHI; G.FILACCHIONI; C. MARTINI; L. TRINCAVELLI; A. LUCACCHINI
1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: synthesis, biological evaluation and molecular modeling study 2005 F.VARANO; D. CATARZI; V. COLOTTA; F. R. CALABRI; O. LENZI; G. FILACCHIONI; A. GALLI; C. COSTAGLI; F. DEFLORIAN; S. MORO
2- Arylpyrazolo[3,4.c]quinolin-4-acylamines as potent and selective human A3 adenosine receptor antagonists. Synthesis, biological evaluation and molecular modeling studies 2006 V. Colotta; D. Catarzi; F. Varano; F. Capelli; O. Lenzi; L. Trincavelli; S. Moro
2-Aryl-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as new potent adenosine human A2A receptor antagonists 2016 Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Dal Ben, D.; Marucci, G.; Buccioni, M.; Volpini, R.; De Vita, T.; Colotta, V. .
2-Aryl-8-chloro-1,2,4-triazolo[1,5-a]quinoxalin-4-amines as highly potent A1 and A3 adenosine receptor antagonists 2005 D.CATARZI; V.COLOTTA; F. VARANO; F.R.CALABRI; O.LENZI; G. FILACCHIONI; L.TRINCAVELLI; C. MARTINI; A.TRALLI; C.MONTOPOLI; S.MORO
2-Arylimidazo[1,2-a]pyrazin-8-amino derivatives as high-affinity fluorescent human A3 adenosine receptor antagonists with potential neuroprotective properties 2013 D. Catarzi; V. Colotta; F. Varano; L. Squarcialupi; K. Varani; A.M. Pugliese; F. Pedata; I. Palchetti
2-Arylpyrazolo[3,4.c]quinolin-4-heteroaroylamines as potent and selective human A3 adenosine receptor antagonists. Synthesis and biological evaluation 2006 D. Catarzi; V. Colotta; F. Varano; F. Capelli; O. Lenzi; K. Varani
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino Derivatives As New Potent and Selective Human A3Adenosine Receptor Antagonists. Molecular Modeling Studies and Pharmacological Evaluation 2013 Lucia Squarcialupi;Vittoria Colotta;Daniela Catarzi;Flavia Varano;Guido Filacchioni;Katia Varani;Carmen Corciulo;Fabrizio Vincenzi;Pier Andrea Borea;Carla Ghelardini;Lorenzo Di Cesare Mannelli;Antonella Ciancetta;Stefano Moro
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives, new potent and selective human A3 adenosine receptor antagonists endowed with protective effect against oxaliplatin-induced apoptosis in rat astrocyte cell cultures 2012 V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; M. Zanardelli; L. Di Cesare Mannelli; C. Ghelardini; S. Paoletta; S. Moro
2-Hydroxy-1,2,4-benzothiadiazin-1,1-dioxide derivatives as new antagonists of ionotropic glutamate receptors 2013 F. Varano; D. Catarzi; V. Colotta; L. Squarcialupi; R. Matucci.
2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a New Scaffold to obtain Potent and Selective Human A3 Adenosine Receptor Antagonists: New Insights into the Receptor-Antagonist Recognition† 2009 O. Lenzi; V. Colotta; D. Catarzi; F. Varano; D. Poli; G. Filacchioni; K. Varani; F. Vincenzi; P. A. Borea; S. Paoletta; E. Morizzo; S. Moro.
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII 2017 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria