PACCHIANO, FABIO

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PACCHIANO, FABIO

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Design, synthesesis and biological evaluation of novel carbonic anhydrase inhibitors against mammalian, bacterial ad fungal isoforms

2011 F. Pacchiano

Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.

2010 F. Pacchiano;M. Aggarwal;B. S. Avvaru;A. H. Robbins;A. Scozzafava;R. McKenna;C. T. Supuran

Targeting Tumor Hypoxia: Suppression of Breast TumorGrowth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

2011 Y.Lou; P.C. McDonald; A.Oloumi; S.Chia; C.Ostlund; A. Ahmadi; A.Kyle; U.auf dem Keller; S.Leung; D.Huntsman; B.Clarke; B.W.Sutherland; D.Waterhouse; M.Bally; C.Roskelley; C.M. Overall; A.Minchinton; F.Pacchiano; F. Carta; A.Scozzafava; N.Touisni; J.-Y.Winum; C.T. Supuran; S.Dedhar

Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis

2011 F. Pacchiano; F. Carta; P.C. McDonald; Y. Lou; D.Vullo; A. Scozzafava; S. Dedhar; and C.T. Supuran

Titolo	Data di pubblicazione	Autore(i)
Design, synthesesis and biological evaluation of novel carbonic anhydrase inhibitors against mammalian, bacterial ad fungal isoforms	2011	F. Pacchiano
Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.	2010	F. Pacchiano;M. Aggarwal;B. S. Avvaru;A. H. Robbins;A. Scozzafava;R. McKenna;C. T. Supuran
Targeting Tumor Hypoxia: Suppression of Breast TumorGrowth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors	2011	Y.Lou; P.C. McDonald; A.Oloumi; S.Chia; C.Ostlund; A. Ahmadi; A.Kyle; U.auf dem Keller; S.Leung; D.Huntsman; B.Clarke; B.W.Sutherland; D.Waterhouse; M.Bally; C.Roskelley; C.M. Overall; A.Minchinton; F.Pacchiano; F. Carta; A.Scozzafava; N.Touisni; J.-Y.Winum; C.T. Supuran; S.Dedhar
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis	2011	F. Pacchiano; F. Carta; P.C. McDonald; Y. Lou; D.Vullo; A. Scozzafava; S. Dedhar; and C.T. Supuran