MANNINI, BENEDETTA
MANNINI, BENEDETTA
Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'
A causative link between the structure of aberrant protein oligomers and their toxicity
2010 S.Campioni;B.Mannini;M.Zampagni;A.Pensalfini;C.Parrini;E.Evangelisti;A.Relini;M.Stefani;C.M.Dobson;C.Cecchi;F.Chiti
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells
2011 Zampagni M; Cascella R; Casamenti F; Grossi C; Evangelisti E; Wright D; Becatti M; Liguri G; Mannini B; Campioni S; Chiti F; Cecchi C.
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
2021 Cataldi R.; Chia S.; Pisani K.; Ruggeri F.S.; Xu C.K.; Sneideris T.; Perni M.; Sarwat S.; Joshi P.; Kumita J.R.; Linse S.; Habchi J.; Knowles T.P.J.; Mannini B.; Dobson C.M.; Vendruscolo M.
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease
2020 Ikenoue T.; Aprile F.A.; Sormanni P.; Ruggeri F.S.; Perni M.; Heller G.T.; Haas C.P.; Middel C.; Limbocker R.; Mannini B.; Michaels T.C.T.; Knowles T.P.J.; Dobson C.M.; Vendruscolo M.
A Relationship between the Structures and Neurotoxic Effects of Aβ Oligomers Stabilized by Different Metal Ions
2024 Chia, Sean; Cataldi, Rodrigo Lessa; Ruggeri, Francesco Simone; Limbocker, Ryan; Condado-Morales, Itzel; Pisani, Katarina; Possenti, Andrea; Linse, Sara; Knowles, Tuomas P. J.; Habchi, Johnny; Mannini, Benedetta; Vendruscolo, Michele
Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N
2013 Francesca Tatini; Anna Maria Pugliese; Chiara Traini; Sandra Niccoli; Giovanna Maraula; Teresa Ed Dami; Benedetta Mannini; Tania Scartabelli; Felicita Pedata; Fiorella Casamenti; Fabrizio Chiti
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors.
2021 Giulia Fani, Benedetta Mannini, Giulia Vecchi, Roberta Cascella, Cristina Cecchi, Christopher M. Dobson, Michele Vendruscolo, Fabrizio Chiti
Bis(indolyl)phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme
2016 Ramshini, Hassan; Mannini, Benedetta; Khodayari, Kaveh; Ebrahim-Habibi, Azadeh; Moghaddasi, Azam Sadat; Tayebee, Reza; Chiti, Fabrizio*
Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity
2017 Mannini, Benedetta; Chiti, Fabrizio
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action
2011 B. Mannini; S. Campioni; M. Boninsegna; E. Palagano; R. Cascella; M. Zampagni; A. Penco; M. Wilson; S. Meehan; C. Roodveldt; A. Relini; C. Cecchi; F. Chiti
Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action
2012 B. Mannini; S. Campioni; M. Boninsegna; A. Penco; R. Cascella; M. Zampagni; M. Wilson; S. Meehan; C. Roodveldt; C. Dobson; A. Relini; C. Cecchi; F. Chiti
Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles
2017 Perni M.; Aprile F.A.; Casford S.; Mannini B.; Sormanni P.; Dobson C.M.; Vendruscolo M.
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers
2019 Mannini, Benedetta; Vecchi, Giulia; Labrador-Garrido, Adahir; Fabre, Bertrand; Fani, Giulia; Munoz Franco, Jaime; Lilley, Kathryn S; Pozo, David; Vendruscolo, Michele; Chiti, Fabrizio; Dobson, Christopher M; Roodveldt, Cintia
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
2021 Leal-Lasarte, Magdalena; Mannini, Benedetta; Chiti, Fabrizio; Vendruscolo, Michele; Dobson, Christopher M; Roodveldt, Cintia; Pozo, David
Early-forming aberrant aggregates in protein deposition diseases: structural characteristics, interaction with molecular chaperones, ability to trigger inflammation
2013 Benedetta Mannini
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations
2016 Cappelli, S; Penco, A; Mannini, Benedetta; Cascella, Roberta; Wilson, M; Ecroyd, H; Li, X; Buxbaum, J; Dobson, Cm; Cecchi, Cristina; Relini, A; Chiti, Fabrizio
Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans
2021 Perni, Michele; Mannini, Benedetta; Xu, Catherine K; Kumita, Janet R; Dobson, Christopher M; Chiti, Fabrizio; Vendruscolo, Michele
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates
2012 T. Saridaki; M. Zampagni; B. Mannini; E. Evangelisti; N. Taddei; C. Cecchi; F. Chiti
Large proteins have a great tendency to aggregate but a low propensity to form amyloid fibrils
2011 H.Ramshini; C.Parrini; A.Relini; M.Zampagni; B.Mannini; A.Pesce; A.A.Saboury; M.Nemat-Gorgani; F.Chiti
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers
2012 B. Mannini; R. Cascella; M. Zampagni; M. van Waarde-Verhagen; S. Meehan; C. Roodveldt; S. Campioni; M. Boninsegna; A. Penco; A. Relini; H.H. Kampinga; C.M. Dobson; M.R. Wilson; C. Cecchi; F. Chiti
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A causative link between the structure of aberrant protein oligomers and their toxicity | 2010 | S.Campioni;B.Mannini;M.Zampagni;A.Pensalfini;C.Parrini;E.Evangelisti;A.Relini;M.Stefani;C.M.Dobson;C.Cecchi;F.Chiti | |
| A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells | 2011 | Zampagni M; Cascella R; Casamenti F; Grossi C; Evangelisti E; Wright D; Becatti M; Liguri G; Mannini B; Campioni S; Chiti F; Cecchi C. | |
| A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers | 2021 | Cataldi R.; Chia S.; Pisani K.; Ruggeri F.S.; Xu C.K.; Sneideris T.; Perni M.; Sarwat S.; Joshi P.; Kumita J.R.; Linse S.; Habchi J.; Knowles T.P.J.; Mannini B.; Dobson C.M.; Vendruscolo M. | |
| A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease | 2020 | Ikenoue T.; Aprile F.A.; Sormanni P.; Ruggeri F.S.; Perni M.; Heller G.T.; Haas C.P.; Middel C.; Limbocker R.; Mannini B.; Michaels T.C.T.; Knowles T.P.J.; Dobson C.M.; Vendruscolo M. | |
| A Relationship between the Structures and Neurotoxic Effects of Aβ Oligomers Stabilized by Different Metal Ions | 2024 | Chia, Sean; Cataldi, Rodrigo Lessa; Ruggeri, Francesco Simone; Limbocker, Ryan; Condado-Morales, Itzel; Pisani, Katarina; Possenti, Andrea; Linse, Sara; Knowles, Tuomas P. J.; Habchi, Johnny; Mannini, Benedetta; Vendruscolo, Michele | |
| Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N | 2013 | Francesca Tatini; Anna Maria Pugliese; Chiara Traini; Sandra Niccoli; Giovanna Maraula; Teresa Ed Dami; Benedetta Mannini; Tania Scartabelli; Felicita Pedata; Fiorella Casamenti; Fabrizio Chiti | |
| Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. | 2021 | Giulia Fani, Benedetta Mannini, Giulia Vecchi, Roberta Cascella, Cristina Cecchi, Christopher M. Dobson, Michele Vendruscolo, Fabrizio Chiti | |
| Bis(indolyl)phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme | 2016 | Ramshini, Hassan; Mannini, Benedetta; Khodayari, Kaveh; Ebrahim-Habibi, Azadeh; Moghaddasi, Azam Sadat; Tayebee, Reza; Chiti, Fabrizio* | |
| Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity | 2017 | Mannini, Benedetta; Chiti, Fabrizio | |
| Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action | 2011 | B. Mannini; S. Campioni; M. Boninsegna; E. Palagano; R. Cascella; M. Zampagni; A. Penco; M. Wilson; S. Meehan; C. Roodveldt; A. Relini; C. Cecchi; F. Chiti | |
| Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action | 2012 | B. Mannini; S. Campioni; M. Boninsegna; A. Penco; R. Cascella; M. Zampagni; M. Wilson; S. Meehan; C. Roodveldt; C. Dobson; A. Relini; C. Cecchi; F. Chiti | |
| Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles | 2017 | Perni M.; Aprile F.A.; Casford S.; Mannini B.; Sormanni P.; Dobson C.M.; Vendruscolo M. | |
| Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers | 2019 | Mannini, Benedetta; Vecchi, Giulia; Labrador-Garrido, Adahir; Fabre, Bertrand; Fani, Giulia; Munoz Franco, Jaime; Lilley, Kathryn S; Pozo, David; Vendruscolo, Michele; Chiti, Fabrizio; Dobson, Christopher M; Roodveldt, Cintia | |
| Distinct responses of human peripheral blood cells to different misfolded protein oligomers | 2021 | Leal-Lasarte, Magdalena; Mannini, Benedetta; Chiti, Fabrizio; Vendruscolo, Michele; Dobson, Christopher M; Roodveldt, Cintia; Pozo, David | |
| Early-forming aberrant aggregates in protein deposition diseases: structural characteristics, interaction with molecular chaperones, ability to trigger inflammation | 2013 | Benedetta Mannini | |
| Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations | 2016 | Cappelli, S; Penco, A; Mannini, Benedetta; Cascella, Roberta; Wilson, M; Ecroyd, H; Li, X; Buxbaum, J; Dobson, Cm; Cecchi, Cristina; Relini, A; Chiti, Fabrizio | |
| Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans | 2021 | Perni, Michele; Mannini, Benedetta; Xu, Catherine K; Kumita, Janet R; Dobson, Christopher M; Chiti, Fabrizio; Vendruscolo, Michele | |
| Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates | 2012 | T. Saridaki; M. Zampagni; B. Mannini; E. Evangelisti; N. Taddei; C. Cecchi; F. Chiti | |
| Large proteins have a great tendency to aggregate but a low propensity to form amyloid fibrils | 2011 | H.Ramshini; C.Parrini; A.Relini; M.Zampagni; B.Mannini; A.Pesce; A.A.Saboury; M.Nemat-Gorgani; F.Chiti | |
| Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers | 2012 | B. Mannini; R. Cascella; M. Zampagni; M. van Waarde-Verhagen; S. Meehan; C. Roodveldt; S. Campioni; M. Boninsegna; A. Penco; A. Relini; H.H. Kampinga; C.M. Dobson; M.R. Wilson; C. Cecchi; F. Chiti |