ARIAS, HUGO RUBEN
ARIAS, HUGO RUBEN
(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop
2022 Arias, Hugo R; Borghese, Cecilia M; Germann, Allison L; Pierce, Spencer R; Bonardi, Alessandro; Nocentini, Alessio; Gratteri, Paola; Thodati, Thanvi M; Lim, Natalie J; Harris, R Adron; Akk, Gustav
Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor
2023 Arias, Hugo R; Pierce, Spencer R; Germann, Allison L; Xu, Sophia Q; Ortells, Marcelo O; Sakamoto, Seiji; Manetti, Dina; Romanelli, Maria Novella; Hamachi, Itaru; Akk, Gustav
Functional and structural interactions of novel acrylamide-based compounds with the α7 nicotinic acetylcholine receptor
2026 Han-Shen Tae , Marcelo O. Ortells , Katarzyna M. Targowska-Duda , Dina Manetti, Maria N. Romanelli, David J. Adams, Hugo R. Arias
Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors
2025 Arias, Hugo R.; Micheli, Laura; Jensen, Anders A.; Galant, Sonya; Vandermoere, Franck; Venturi, Daniel; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Marin, Philippe; Di Cesare Mannelli, Lorenzo
Non-hallucinogenic compounds derived from iboga alkaloids alleviate neruopathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation
2024 Hugo R. Arias, Laura Micheli, Deborah Rudin, Ophelie Bento, Saskia Borsdorf, Clara Campi, Philippe Marin, Evgeni Ponimaskin, Dina Manetti, Maria Novella Romanelli, Carla Ghelardini, Matthias E. Liechti, Lorenzo Di Cesare Mannelli
Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex
2024 Looschen K.; Khatri S.N.; Maulik M.; Salisbury C.; Carman A.F.; Corriveau K.; Smith C.; Manetti D.; Romanelli M.N.; Arias H.R.; Gipson C.D.; Mitra S.
Significance of the nicotinic alpha7 receptor in cognition and antipsychotic-like behavior in the rat
2017 Wadenberg, Marie-Louise G; Manetti, Dina; Romanelli, Maria Novella; Arias, Hugo R.
The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor
2023 Arias, Hugo R; Tae, Han-Shen; Micheli, Laura; Yousuf, Arsalan; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Adams, David J; Di Cesare Mannelli, Lorenzo
The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation
2024 Arias H.R.; Rudin D.; Hines D.J.; Contreras A.; Gulsevin A.; Manetti D.; Anouar Y.; De Deurwaerdere P.; Meiler J.; Romanelli M.N.; Liechti M.E.; Chagraoui A.
The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission
2025 Arias, Hugo R.; Rudin, Deborah; Luethi, Dino; Valenta, Jan; Leśniak, Anna; Czartoryska, Zofia; Olejarz-Maciej, Agnieszka; Doroz-Płonka, Agata; Manetti, Dina; De Deurwaerdère, Philippe; Romanelli, Maria Novella; Handzlik, Jadwiga; Liechti, Matthias E.; Chagraoui, Abdeslam
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop | 2022 | Arias, Hugo R; Borghese, Cecilia M; Germann, Allison L; Pierce, Spencer R; Bonardi, Alessandro; Nocentini, Alessio; Gratteri, Paola; Thodati, Thanvi M; Lim, Natalie J; Harris, R Adron; Akk, Gustav | |
| Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor | 2023 | Arias, Hugo R; Pierce, Spencer R; Germann, Allison L; Xu, Sophia Q; Ortells, Marcelo O; Sakamoto, Seiji; Manetti, Dina; Romanelli, Maria Novella; Hamachi, Itaru; Akk, Gustav | |
| Functional and structural interactions of novel acrylamide-based compounds with the α7 nicotinic acetylcholine receptor | 2026 | Han-Shen Tae , Marcelo O. Ortells , Katarzyna M. Targowska-Duda , Dina Manetti, Maria N. Romanelli, David J. Adams, Hugo R. Arias | |
| Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors | 2025 | Arias, Hugo R.; Micheli, Laura; Jensen, Anders A.; Galant, Sonya; Vandermoere, Franck; Venturi, Daniel; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Marin, Philippe; Di Cesare Mannelli, Lorenzo | |
| Non-hallucinogenic compounds derived from iboga alkaloids alleviate neruopathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation | 2024 | Hugo R. Arias, Laura Micheli, Deborah Rudin, Ophelie Bento, Saskia Borsdorf, Clara Campi, Philippe Marin, Evgeni Ponimaskin, Dina Manetti, Maria Novella Romanelli, Carla Ghelardini, Matthias E. Liechti, Lorenzo Di Cesare Mannelli | |
| Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex | 2024 | Looschen K.; Khatri S.N.; Maulik M.; Salisbury C.; Carman A.F.; Corriveau K.; Smith C.; Manetti D.; Romanelli M.N.; Arias H.R.; Gipson C.D.; Mitra S. | |
| Significance of the nicotinic alpha7 receptor in cognition and antipsychotic-like behavior in the rat | 2017 | Wadenberg, Marie-Louise G; Manetti, Dina; Romanelli, Maria Novella; Arias, Hugo R. | |
| The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor | 2023 | Arias, Hugo R; Tae, Han-Shen; Micheli, Laura; Yousuf, Arsalan; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Adams, David J; Di Cesare Mannelli, Lorenzo | |
| The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation | 2024 | Arias H.R.; Rudin D.; Hines D.J.; Contreras A.; Gulsevin A.; Manetti D.; Anouar Y.; De Deurwaerdere P.; Meiler J.; Romanelli M.N.; Liechti M.E.; Chagraoui A. | |
| The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission | 2025 | Arias, Hugo R.; Rudin, Deborah; Luethi, Dino; Valenta, Jan; Leśniak, Anna; Czartoryska, Zofia; Olejarz-Maciej, Agnieszka; Doroz-Płonka, Agata; Manetti, Dina; De Deurwaerdère, Philippe; Romanelli, Maria Novella; Handzlik, Jadwiga; Liechti, Matthias E.; Chagraoui, Abdeslam |