The presence of numerous CD4+ CD161+ lymphocytes in perianal fistula in Crohn's disease and in hidradenitis suppurativa lesion curettages suggests that these cells may play a pathogenic role, and candidates CD161 as a possible biological target for medical treatment
Perianal Crohn's disease and hidradenitis suppurativa: A possible common immunological scenario / Giudici, Francesco; Maggi, Laura; Santi, Raffaella; Cosmi, Lorenzo; Scaletti, Cristina; Annunziato, Francesco; Nesi, Gabriella; Barra, Giusi; Bassotti, Gabrio; De Palma, Raffaele; Tonelli, Francesco. - In: CLINICAL AND MOLECULAR ALLERGY. - ISSN 1476-7961. - ELETTRONICO. - 13:(2015), pp. 1-6. [10.1186/s12948-015-0018-8]
Perianal Crohn's disease and hidradenitis suppurativa: A possible common immunological scenario
Giudici, Francesco;Maggi, Laura;Santi, Raffaella;Cosmi, Lorenzo;Scaletti, Cristina;Annunziato, Francesco;Nesi, Gabriella;Tonelli, Francesco
2015
Abstract
The presence of numerous CD4+ CD161+ lymphocytes in perianal fistula in Crohn's disease and in hidradenitis suppurativa lesion curettages suggests that these cells may play a pathogenic role, and candidates CD161 as a possible biological target for medical treatment
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