In systemic sclerosis (SSc), clinical evidence has shown that Bosentan may foster the regeneration of the peripheral microcirculatory network. The aim of this study was to verify in vitro the influence of Bosentan on the angiogenic performance of dermal microvascular endothelial cells (MVECs) and its possible capacity to counteract the antiangiogenic effects of SSc sera.

Bosentan blocks the antiangiogenic effects of sera from systemic sclerosis patients: an in vitro study / Romano, Eloisa; Bellando-Randone, Silvia; Manetti, Mirko; Bruni, Cosimo; Lepri, Gemma; Matucci-Cerinic, Marco; Guiducci, Serena. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - STAMPA. - 33 Suppl 91:(2015), pp. 148-152.

Bosentan blocks the antiangiogenic effects of sera from systemic sclerosis patients: an in vitro study

ROMANO, ELOISA;BELLANDO RANDONE, SILVIA;MANETTI, MIRKO;BRUNI, COSIMO;LEPRI, GEMMA;MATUCCI CERINIC, MARCO;GUIDUCCI, SERENA
2015

Abstract

In systemic sclerosis (SSc), clinical evidence has shown that Bosentan may foster the regeneration of the peripheral microcirculatory network. The aim of this study was to verify in vitro the influence of Bosentan on the angiogenic performance of dermal microvascular endothelial cells (MVECs) and its possible capacity to counteract the antiangiogenic effects of SSc sera.
2015
33 Suppl 91
148
152
Goal 3: Good health and well-being for people
Romano, Eloisa; Bellando-Randone, Silvia; Manetti, Mirko; Bruni, Cosimo; Lepri, Gemma; Matucci-Cerinic, Marco; Guiducci, Serena
1a - Articolo su rivista
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1006890
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