Natural killer (NK) cells number, phenotypes and function have been evaluated in many studies in adults with hepatitis C as compared with healthy controls or dynamically during interferon-based and interferon-free treatments. Overall, in adults with chronic infection number of circulating NK cells has been reported to be lower when compared to spontaneous resolvers and healthy subjects. Different studies yielded inconsistent findings due to patient and virus heterogeneity.
Altered natural killer cells subsets distribution in children with hepatitis C following vertical transmission / Indolfi, G; Mangone, G; Moriondo, M; Serranti, D; Bartolini, E; Azzari, C; Resti, M. - In: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. - ISSN 0269-2813. - STAMPA. - 43:(2016), pp. 125-133. [10.1111/apt.13430]
Altered natural killer cells subsets distribution in children with hepatitis C following vertical transmission
INDOLFI, GIUSEPPE;MANGONE, GIUSI;MORIONDO, MARIA;SERRANTI, DANIELE;BARTOLINI, ELISA;AZZARI, CHIARA;RESTI, MASSIMO
2016
Abstract
Natural killer (NK) cells number, phenotypes and function have been evaluated in many studies in adults with hepatitis C as compared with healthy controls or dynamically during interferon-based and interferon-free treatments. Overall, in adults with chronic infection number of circulating NK cells has been reported to be lower when compared to spontaneous resolvers and healthy subjects. Different studies yielded inconsistent findings due to patient and virus heterogeneity.
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