Commercially available lyophilized microbial standards are expensive and subject to reduction in cell viability due to freeze-drying stress. Here we introduce an inexpensive and straightforward method for in-house microbial standard preparation and cryoconservation that preserves constant cell titre and cell viability over 14 months.
A new method for long-term storage of titred microbial standard solutions suitable for microbiologic quality control activities of pharmaceutical companies / C. Chiellini; Mocali, S.; Fani, R.; Ferro, I.; Bruschi, S.; Pinzani, A.. - In: JOURNAL OF MICROBIOLOGICAL METHODS. - ISSN 0167-7012. - STAMPA. - 127:(2016), pp. 10-12.
A new method for long-term storage of titred microbial standard solutions suitable for microbiologic quality control activities of pharmaceutical companies
FANI, RENATO;
2016
Abstract
Commercially available lyophilized microbial standards are expensive and subject to reduction in cell viability due to freeze-drying stress. Here we introduce an inexpensive and straightforward method for in-house microbial standard preparation and cryoconservation that preserves constant cell titre and cell viability over 14 months.
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Chiellini et al 2016 - J Microbiological Methods - A new method for long-term storage of titred microbial standard.pdf
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