The effects of ischemia on the cerebral white matter structure seldom have been studied possibly because white matter is generally considered less vulnerable to ischemia than gray matter. The objective of this study was to evaluate the early (< or = 24 hours) structural effects of experimental focal ischemia on the cerebral white matter of the rat as a preliminary step to investigating human conditions of unknown pathogenesis that are characterized by selective damage to the white matter.
Cerebral white matter is highly vulnerable to ischemia / Pantoni, L; Garcia, J H; Gutierrez, J A. - In: STROKE. - ISSN 0039-2499. - ELETTRONICO. - 27:(1996), pp. 1641; discussion 1647-1647.
Cerebral white matter is highly vulnerable to ischemia
PANTONI, LEONARDO;
1996
Abstract
The effects of ischemia on the cerebral white matter structure seldom have been studied possibly because white matter is generally considered less vulnerable to ischemia than gray matter. The objective of this study was to evaluate the early (< or = 24 hours) structural effects of experimental focal ischemia on the cerebral white matter of the rat as a preliminary step to investigating human conditions of unknown pathogenesis that are characterized by selective damage to the white matter.
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