Ameloblastoma is a benign odontogenic tumour that may exhibit aggressive biological behaviour with local recurrence and metastasis following initial surgical resection. Surgery is the most acceptable modality of treatment, even if a biological approach is currently on study. We report a case of maxillary ameloblastoma with development of neck and brain metastases after repeated local recurrences. Molecular analysis was performed with the aim to better characterize this neoplasm and its peculiar behaviour.
Metastasizing Maxillary Ameloblastoma: Report of a Case with Molecular Characterization / Rotellini, Matteo; Maggiore, Giandomenico; Trovati, Massimo; Saraceno, Massimo Squadrelli; Franchi, Alessandro. - In: EJOURNAL OF ORAL MAXILLOFACIAL RESEARCH. - ISSN 2029-283X. - ELETTRONICO. - 7:(2016), pp. e5-.. [10.5037/jomr.2016.7105]
Metastasizing Maxillary Ameloblastoma: Report of a Case with Molecular Characterization
ROTELLINI, MATTEO;FRANCHI, ALESSANDRO
2016
Abstract
Ameloblastoma is a benign odontogenic tumour that may exhibit aggressive biological behaviour with local recurrence and metastasis following initial surgical resection. Surgery is the most acceptable modality of treatment, even if a biological approach is currently on study. We report a case of maxillary ameloblastoma with development of neck and brain metastases after repeated local recurrences. Molecular analysis was performed with the aim to better characterize this neoplasm and its peculiar behaviour.
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