OPEN VERSUS LAPAROSCOPIC PARTIAL NEPHRECTOMY FOR CLINICAL T1A RENAL TUMORS: SURGICAL, FUNCTIONAL AND TRIFECTA OUTCOMES BASED ON A MATCHED-PAIR COMPARISON OF 280 PATIENTS (RECORD PROJECT)

Scopo del lavoro To report a match-pair comparative analysis between open (OPN) and laparoscopic partial nephrectomy (LPN) for clinical (c) T1a renal masses from a large prospective multicenter dataset. Materiali e metodi The RECORd Project is a 4-Year prospective observational multicenter study promoted by the Italian Society of Urology. The study includes all patients who underwent OPN and LPN for kidney cancer between January 2009 and January 2011 at 19 Italian centers. Open and Laparoscopic groups were compared regarding clinical, surgical, pathologic, functional results and TRIFECTA outcome (WIT 25 minutes, Surgical Complications (SC) and the achievement of the TRIFECTA outcome. Risultati Overall, 301 patients had OPN and 149 LPN. Groups were matched 1:1 (140 matched pairs) for Clinical Diameter, Tumor Side and Type of Indication. The achievement of the TRIFECTA outcome was comparable between the OPN vs LPN group (78.6% vs 74.3%, p: ns). Overall, 46 Total Complications after OPN vs LPN (17.9% vs 15%; p:ns) occurred. At multivariate analysis the surgical approach (Laparoscopic vs Open) was not a predictor of a negative TRIFECTA and SC. Whereas, the Laparoscopic approach was associated with a significantly mean longer WIT (19.9 vs 15.1 min; p25 minutes (RR: 6.29, 95%CI: 2.47-16.07; p Discussione Trifecta should be a routine goal during partial nephrectomy. Conclusioni No significant difference in achieving the TRIFECTA outcome (WIT