Humanmilk samples were collected from67mothers in 2014 at a Primary Care Centre inMurcia (Spain) and analyzed for perfluorinated carboxylic acids (PFCAs). Concentrations measured for perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA) and perfluorododecanoic acid (PFDoDA) ranged from bLOQ (b10 ng/L) to 397 ng/L with a mean concentration of 66 ± 68 ng/L and a median of 29 ng/L. The presence of these compounds was revealed in 50 samples out of 67 analyzed. Influence of number of pregnancies and food habits on PFCAs concentrations was also investigated. Statistically significant differences in PFCA levels were found when the women were divided into maternal age classes and into the categories primiparae and multiparae. A greater transfer of PFC during breastfeeding by primiparous was evidenced and thus a higher exposure to these contaminants for the first child. Moreover, it was possible to hypothesize that the content of PFCs is in general correlated to the eating habits of donors and, in particular, with the fish consumption. Finally, PFOA daily intakes and risk index (RI) were estimated for the first six months of life and we found that ingestion rates of PFOA did not exceed the tolerable daily intake (TDI) recommended by the European Food Safety Authority (EFSA).
Perfluorinated carboxylic acids in human breast milk from Spain and estimation of infant's daily intake / Motas Guzmàn, Miguel; Clementini, Chiara; Pérez-Cárceles, Maria Dolores; Jiménez Rejón, Sandra; Cascone, Aurora; Martellini, Tania; Guerranti, Cristiana; Cincinelli, Alessandra. - In: SCIENCE OF THE TOTAL ENVIRONMENT. - ISSN 0048-9697. - STAMPA. - 544:(2016), pp. 595-600. [10.1016/j.scitotenv.2015.11.059]
Perfluorinated carboxylic acids in human breast milk from Spain and estimation of infant's daily intake
MARTELLINI, TANIA;CINCINELLI, ALESSANDRA
2016
Abstract
Humanmilk samples were collected from67mothers in 2014 at a Primary Care Centre inMurcia (Spain) and analyzed for perfluorinated carboxylic acids (PFCAs). Concentrations measured for perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA) and perfluorododecanoic acid (PFDoDA) ranged from bLOQ (b10 ng/L) to 397 ng/L with a mean concentration of 66 ± 68 ng/L and a median of 29 ng/L. The presence of these compounds was revealed in 50 samples out of 67 analyzed. Influence of number of pregnancies and food habits on PFCAs concentrations was also investigated. Statistically significant differences in PFCA levels were found when the women were divided into maternal age classes and into the categories primiparae and multiparae. A greater transfer of PFC during breastfeeding by primiparous was evidenced and thus a higher exposure to these contaminants for the first child. Moreover, it was possible to hypothesize that the content of PFCs is in general correlated to the eating habits of donors and, in particular, with the fish consumption. Finally, PFOA daily intakes and risk index (RI) were estimated for the first six months of life and we found that ingestion rates of PFOA did not exceed the tolerable daily intake (TDI) recommended by the European Food Safety Authority (EFSA).File | Dimensione | Formato | |
---|---|---|---|
2016 Cincinelli milk.pdf
Accesso chiuso
Tipologia:
Pdf editoriale (Version of record)
Licenza:
Tutti i diritti riservati
Dimensione
490.92 kB
Formato
Adobe PDF
|
490.92 kB | Adobe PDF | Richiedi una copia |
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.