DNA copy number alterations (CNAs) and gene expression changes have amply been encountered in colorectal cancers (CRCs), but the extent at which CNAs affect gene expression, as well as their relevance for tumor development, are still poorly defined. Here we aimed at assessing the clinical relevance of these parameters in a 10 year follow-up study.
DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up / Bigagli, Elisabetta; De Filippo, Carlotta; Castagnini, Cinzia; Toti, Simona; Acquadro, Francesco; Giudici, Francesco; Fazi, Marilena; Dolara, Piero; Messerini, Luca; Tonelli, Francesco; Luceri, Cristina. - In: CELLULAR ONCOLOGY. - ISSN 2211-3428. - ELETTRONICO. - (2016), pp. 0-0. [10.1007/s13402-016-0299-z]
DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up
BIGAGLI, ELISABETTA;DE FILIPPO, CARLOTTA;CASTAGNINI, CINZIA;TOTI, SIMONA;GIUDICI, FRANCESCO;FAZI, MARILENA;DOLARA, PIERO;MESSERINI, LUCA;TONELLI, FRANCESCO;LUCERI, CRISTINA
2016
Abstract
DNA copy number alterations (CNAs) and gene expression changes have amply been encountered in colorectal cancers (CRCs), but the extent at which CNAs affect gene expression, as well as their relevance for tumor development, are still poorly defined. Here we aimed at assessing the clinical relevance of these parameters in a 10 year follow-up study.
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