CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but their production by human T cells, has never been reported.
Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients / Capone, Manuela; Maggi, Laura; Santarlasci, Veronica; Rossi, Maria Caterina; Mazzoni, Alessio; Montaini, Gianni; Cimaz, Rolando; Ramazzotti, Matteo; Piccinni, Marie-Pierre; Barra, Giusi; De Palma, Raffaele; Liotta, Francesco; Maggi, Enrico; Romagnani, Sergio; Annunziato, Francesco; Cosmi, Lorenzo. - In: CLINICAL AND MOLECULAR ALLERGY. - ISSN 1476-7961. - ELETTRONICO. - 14:(2016), pp. 16-16. [10.1186/s12948-016-0053-0]
Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients
Capone, Manuela;Maggi, Laura;Mazzoni, Alessio;Cimaz, Rolando;Ramazzotti, Matteo;Piccinni, Marie-Pierre;Liotta, Francesco;Maggi, Enrico;Romagnani, Sergio;Annunziato, Francesco;Cosmi, Lorenzo
2016
Abstract
CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but their production by human T cells, has never been reported.
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2016 - Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients.pdf
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