Systemic sclerosis (SSc) is a connective tissue disease frequently associated with Raynaud’s Phenomenon (RP). Among possible pharmacological treatments, phosphodiesterase 5 inhibitors are considered in cases of severe non -responsive RP. We present the case of a male SSc patient wh presented with critical finger ischemia and concomitant appearance of myocardial fibrosis after sudden interruption of sildenafil treatment.
Critical finger ischemia and myocardial fibrosis development after sudden interruption of sildenafil treatment in a systemic sclerosis patient / Bruni, C.; Bellando-Randone, S.; Gargani, L.; Picano, E.; Pingitore, A.; Matucci-Cerinic, M.; Guiducci, S.. - In: REUMATISMO. - ISSN 0048-7449. - ELETTRONICO. - 68:(2016), pp. 109-111. [10.4081/reumatismo.2016.889]
Critical finger ischemia and myocardial fibrosis development after sudden interruption of sildenafil treatment in a systemic sclerosis patient.
BRUNI, COSIMO;BELLANDO RANDONE, SILVIA;MATUCCI CERINIC, MARCO;GUIDUCCI, SERENA
2016
Abstract
Systemic sclerosis (SSc) is a connective tissue disease frequently associated with Raynaud’s Phenomenon (RP). Among possible pharmacological treatments, phosphodiesterase 5 inhibitors are considered in cases of severe non -responsive RP. We present the case of a male SSc patient wh presented with critical finger ischemia and concomitant appearance of myocardial fibrosis after sudden interruption of sildenafil treatment.
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