Among infected contacts, preventive therapy promises to reduce the risk of disease progression. This is supported by observational cohort studies, but randomized trials are urgently needed to confirm these observations and guide policy formulation. Substantial investment in MDR/XDR-TB prevention and care will be critical if the ambitious global goal of TB elimination is to be realized.
Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases / Fox, G.J; Schaaf, H.S.; Mandalakas, A.; Chiappini, E.; Zumla, A.; Marais, B.J.. - In: CLINICAL MICROBIOLOGY AND INFECTION. - ISSN 1198-743X. - STAMPA. - (2016), pp. ??-??. [10.1016/j.cmi.2016.08.024]
Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases
CHIAPPINI, ELENA;
2016
Abstract
Among infected contacts, preventive therapy promises to reduce the risk of disease progression. This is supported by observational cohort studies, but randomized trials are urgently needed to confirm these observations and guide policy formulation. Substantial investment in MDR/XDR-TB prevention and care will be critical if the ambitious global goal of TB elimination is to be realized.
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