Pyridine and adenine nucleotide levels were measured in Friend erythroleukaemia cells (FELC) stimulated to growth and induced to differentiate by hexamethylene bisacetamide (HMBA) and N'-methylnicotinamide (N'-MNAM). A three- to fourfold increase in the NADP(H) was found to parallel cell growth stimulation in both the presence and absence of differentiation inducers.A decrease in poly(ADP-ribose) polymerase activity was also fou nd in differentiated cells in contrast to controls.
CHANGES IN PYRIDINE AND ADENINE NUCLEOTIDE LEVELS IN FRIEND ERYTHROLEUKAEMIA CELLS DURING GROWTH AND DIFFERENTIATION / R. CALDINI; M. CHEVANNE; L. MAGNELLI. - In: JOURNAL OF CELLULAR PHYSIOLOGY. - ISSN 0021-9541. - STAMPA. - 151:(1992), pp. 172-179. [10.1002/jcp.1041510122]
CHANGES IN PYRIDINE AND ADENINE NUCLEOTIDE LEVELS IN FRIEND ERYTHROLEUKAEMIA CELLS DURING GROWTH AND DIFFERENTIATION.
CALDINI, RICCARDO;CHEVANNE, MARTA;MAGNELLI, LUCIA
1992
Abstract
Pyridine and adenine nucleotide levels were measured in Friend erythroleukaemia cells (FELC) stimulated to growth and induced to differentiate by hexamethylene bisacetamide (HMBA) and N'-methylnicotinamide (N'-MNAM). A three- to fourfold increase in the NADP(H) was found to parallel cell growth stimulation in both the presence and absence of differentiation inducers.A decrease in poly(ADP-ribose) polymerase activity was also fou nd in differentiated cells in contrast to controls.
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