A prototype of proton Computed Tomography (pCT) system for hadron-therapy has been manufactured and tested in a 175 MeV proton beam with a non-homogeneous phantom designed to simulate high contrast material. BI-SART reconstruction algorithms have been implemented with GPU parallelism, taking into account of most likely paths of protons in matter. Reconstructed tomography images with density resolutions r.m.s. down to similar to 1% and spatial resolutions <1 mm, achieved within processing times of similar to 15' for a 512 x 512 pixels image prove that this technique will be beneficial if used instead of X-CT in hadron-therapy.
Proton computed tomography images with algebraic reconstruction / Bruzzi, M.; Civinini, C.; Scaringella, M.; Bonanno, D.; Brianzi, M.; Carpinelli, M.; Cirrone, G.A.P.; Cuttone, G.; Presti, D. Lo; Maccioni, G.; Pallotta, S.; Randazzo, N.; Romano, F.; Sipala, V.; Talamonti, C.; Vanzi, E.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - STAMPA. - 845:(2017), pp. 652-655. [10.1016/j.nima.2016.05.056]
Proton computed tomography images with algebraic reconstruction
BRUZZI, MARA;SCARINGELLA, MONICA;PALLOTTA, STEFANIA;TALAMONTI, CINZIA;
2017
Abstract
A prototype of proton Computed Tomography (pCT) system for hadron-therapy has been manufactured and tested in a 175 MeV proton beam with a non-homogeneous phantom designed to simulate high contrast material. BI-SART reconstruction algorithms have been implemented with GPU parallelism, taking into account of most likely paths of protons in matter. Reconstructed tomography images with density resolutions r.m.s. down to similar to 1% and spatial resolutions <1 mm, achieved within processing times of similar to 15' for a 512 x 512 pixels image prove that this technique will be beneficial if used instead of X-CT in hadron-therapy.
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