New oxathiazinane dioxides have been derived from D- and L-serine and tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. (5R)-5-(4-(4'-Bromomethyl)phenyl)benzyloxymethyl-[1,3,4]-oxathiazinane- 3,3-dioxide showed a cytotoxicity of IC50 approximate to 10 mu M.

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity / Borcard, Françoise; Baud, Matthias; Bello, Claudia; Dal Bello, Giovanna; Grossi, Francesco; Pronzato, Paolo; Cea, Michele; Nencioni, Alessio; Vogel, Pierre. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - ELETTRONICO. - 20:(2010), pp. 5353-5356. [10.1016/j.bmcl.2009.09.019]

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity

BELLO, CLAUDIA;
2010

Abstract

New oxathiazinane dioxides have been derived from D- and L-serine and tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. (5R)-5-(4-(4'-Bromomethyl)phenyl)benzyloxymethyl-[1,3,4]-oxathiazinane- 3,3-dioxide showed a cytotoxicity of IC50 approximate to 10 mu M.
2010
20
5353
5356
Borcard, Françoise; Baud, Matthias; Bello, Claudia; Dal Bello, Giovanna; Grossi, Francesco; Pronzato, Paolo; Cea, Michele; Nencioni, Alessio; Vogel, Pierre
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1093176
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