SAA-amyloidosis was present in the aortic valve from an AKU patient and colocalized with ochronotic pigment as well as with tissue calcification, lipid oxidation, macrophages infiltration, cell death, and tissue degeneration.
Amyloidosis, inflammation, and oxidative stress in the heart of an alkaptonuric patient / Millucci, Lia; Ghezzi, Lorenzo; Paccagnini, Eugenio; Giorgetti, Giovanna; Viti, Cecilia; Braconi, Daniela; Laschi, Marcella; Geminiani, Michela; Soldani, Patrizia; Lupetti, Pietro; Orlandini, Maurizio; Benvenuti, Chiara; Perfetto, Federico; Spreafico, Adriano; Bernardini, Giulia; Santucci, Annalisa. - In: MEDIATORS OF INFLAMMATION. - ISSN 0962-9351. - STAMPA. - 2014:(2014), pp. 258471-258482. [10.1155/2014/258471]
Amyloidosis, inflammation, and oxidative stress in the heart of an alkaptonuric patient
Perfetto, Federico;Bernardini, Giulia
;Santucci, Annalisa
2014
Abstract
SAA-amyloidosis was present in the aortic valve from an AKU patient and colocalized with ochronotic pigment as well as with tissue calcification, lipid oxidation, macrophages infiltration, cell death, and tissue degeneration.
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