We have replicated the findings of Alvarado-Cardenas et al. in our cohort of anti-HMGCR myositis patients, confirming the high specificity and sensibility of the rat liver IF pattern, especially when compared to the previously reported HEp-2 anti-HMGCR pattern. Nonetheless, we agree on the value of this finding in easing the diagnosis of statin-associated myositis in standard laboratory settings.
Anti-HMGCR and anti-DFS70 antibodies immunofluorescence patterns / Palterer, Boaz; Cammelli, Daniele; Vitiello, Gianfranco; Giudizi, Maria Grazia. - In: AUTOIMMUNITY REVIEWS. - ISSN 1568-9972. - STAMPA. - 16:(2017), pp. 321-322. [10.1016/j.autrev.2017.01.002]
Anti-HMGCR and anti-DFS70 antibodies immunofluorescence patterns
Palterer, Boaz;Vitiello, Gianfranco;Giudizi, Maria Grazia
2017
Abstract
We have replicated the findings of Alvarado-Cardenas et al. in our cohort of anti-HMGCR myositis patients, confirming the high specificity and sensibility of the rat liver IF pattern, especially when compared to the previously reported HEp-2 anti-HMGCR pattern. Nonetheless, we agree on the value of this finding in easing the diagnosis of statin-associated myositis in standard laboratory settings.
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