Acute graft vs host disease is an uncommon and usually fatal complication of lung transplant for which no effective therapy exists. All 8 patients with grade 3 to 4 acute graft vs host disease after lung transplantation described in literature died within 208 days. We report a patient with grade 3 to 4 acute graft vs host disease after bilateral lung transplantation who was successfully treated with high-dose corticosteroids after basiliximab and extracorporeal photopheresis were unsuccessful.
Severe acute graft versus host disease after lung transplant: report of a case successfully treated with high dose corticosteroids / Fossi, Antonella; Voltolini, Luca; Filippi, Rita; Luzzi, Luca; Pasini, Franco Laghi; Marchi, Bruna; Gotti, Giuseppe; Rottoli, Paola. - In: The Journal of Heart and Lung Transplantation. - ELETTRONICO. - 28:(2009), pp. 508-510. [10.1016/j.healun.2009.01.023]
Severe acute graft versus host disease after lung transplant: report of a case successfully treated with high dose corticosteroids
Voltolini, Luca;
2009
Abstract
Acute graft vs host disease is an uncommon and usually fatal complication of lung transplant for which no effective therapy exists. All 8 patients with grade 3 to 4 acute graft vs host disease after lung transplantation described in literature died within 208 days. We report a patient with grade 3 to 4 acute graft vs host disease after bilateral lung transplantation who was successfully treated with high-dose corticosteroids after basiliximab and extracorporeal photopheresis were unsuccessful.
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