The treatment of both Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL) frequently results in residual masses [1] . A high-prognostic-value imaging modality is needed to assess the response to treatment and identify patients with active disease within the residual mass. Positron emission tomography/computed tomography (PET/CT) allows for a complete assessment of the whole body and is now considered an essential tool to evaluate the posttreatment response in fluorodeoxyglucose (FDG)-avid lymphoma [2] , although its accuracy is challenging. In long-term follow-up, often in young patients, an important issue to consider is the exposure to ionizing radiation. The mean effective dose of PET/CT examinations is 19.6 ± 6.1 mSv [3] , corresponding with the radiation of about 1,000 chest X-rays and 10 head CTs [4] . Few studies have investigated the role of advanced magnetic resonance (MR) techniques by the 2 quantitative parameters, diffusion-weighted imaging (DwI) and perfusion-weighted imaging (PwI). DwI is able to provide an assessment of tumor cellular cramming, while PwI can quantitatively evaluate the combined effects of plasma blood flow, permeability, and capillary surface area.

Diffusion-Weighted and Perfusion-Weighted MRI to Evaluate Therapeutic Response in Lymphoma: A Comparison with FDG-PET/CT / Calistri, Linda; Puccini, Benedetta; Berti, Valentina; Grazzini, Giulia; Nardi, Cosimo; Rigacci, Luigi; Colagrande, Stefano. - In: ACTA HAEMATOLOGICA. - ISSN 0001-5792. - ELETTRONICO. - 139:(2018), pp. 74-76. [10.1159/000485548]

Diffusion-Weighted and Perfusion-Weighted MRI to Evaluate Therapeutic Response in Lymphoma: A Comparison with FDG-PET/CT

Calistri, Linda
;
Puccini, Benedetta;Berti, Valentina;Grazzini, Giulia;Nardi, Cosimo;Rigacci, Luigi;Colagrande, Stefano
2018

Abstract

The treatment of both Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL) frequently results in residual masses [1] . A high-prognostic-value imaging modality is needed to assess the response to treatment and identify patients with active disease within the residual mass. Positron emission tomography/computed tomography (PET/CT) allows for a complete assessment of the whole body and is now considered an essential tool to evaluate the posttreatment response in fluorodeoxyglucose (FDG)-avid lymphoma [2] , although its accuracy is challenging. In long-term follow-up, often in young patients, an important issue to consider is the exposure to ionizing radiation. The mean effective dose of PET/CT examinations is 19.6 ± 6.1 mSv [3] , corresponding with the radiation of about 1,000 chest X-rays and 10 head CTs [4] . Few studies have investigated the role of advanced magnetic resonance (MR) techniques by the 2 quantitative parameters, diffusion-weighted imaging (DwI) and perfusion-weighted imaging (PwI). DwI is able to provide an assessment of tumor cellular cramming, while PwI can quantitatively evaluate the combined effects of plasma blood flow, permeability, and capillary surface area.
2018
139
74
76
Calistri, Linda; Puccini, Benedetta; Berti, Valentina; Grazzini, Giulia; Nardi, Cosimo; Rigacci, Luigi; Colagrande, Stefano
File in questo prodotto:
File Dimensione Formato  
zzAHA485548.pdf

Accesso chiuso

Descrizione: Articolo principale
Tipologia: Pdf editoriale (Version of record)
Licenza: Tutti i diritti riservati
Dimensione 88.95 kB
Formato Adobe PDF
88.95 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1110057
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact